ALMTD_ARATH
ID ALMTD_ARATH Reviewed; 539 AA.
AC Q9LS23; Q5XV18; Q5XV19;
DT 30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Aluminum-activated malate transporter 13;
DE Short=AtALMT13;
GN Name=ALMT13; OrderedLocusNames=At5g46600; ORFNames=F10E10.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=cv. Columbia;
RA Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16740662; DOI=10.1073/pnas.0602868103;
RA Hoekenga O.A., Maron L.G., Pineros M.A., Cancado G.M., Shaff J.,
RA Kobayashi Y., Ryan P.R., Dong B., Delhaize E., Sasaki T., Matsumoto H.,
RA Yamamoto Y., Koyama H., Kochian L.V.;
RT "AtALMT1, which encodes a malate transporter, is identified as one of
RT several genes critical for aluminum tolerance in Arabidopsis.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:9738-9743(2006).
CC -!- FUNCTION: Malate transporter. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9LS23-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9LS23-2; Sequence=VSP_040187, VSP_040188;
CC -!- SIMILARITY: Belongs to the aromatic acid exporter (TC 2.A.85) family.
CC {ECO:0000305}.
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DR EMBL; AB028605; BAA97531.1; -; Genomic_DNA.
DR EMBL; CP002688; AED95402.1; -; Genomic_DNA.
DR EMBL; AY735703; AAU44573.1; -; mRNA.
DR EMBL; AY735704; AAU44574.1; -; mRNA.
DR EMBL; AY954875; AAX55201.1; -; mRNA.
DR RefSeq; NP_199472.1; NM_124030.3. [Q9LS23-1]
DR AlphaFoldDB; Q9LS23; -.
DR SMR; Q9LS23; -.
DR STRING; 3702.AT5G46600.1; -.
DR iPTMnet; Q9LS23; -.
DR PaxDb; Q9LS23; -.
DR PRIDE; Q9LS23; -.
DR EnsemblPlants; AT5G46600.1; AT5G46600.1; AT5G46600. [Q9LS23-1]
DR GeneID; 834703; -.
DR Gramene; AT5G46600.1; AT5G46600.1; AT5G46600. [Q9LS23-1]
DR KEGG; ath:AT5G46600; -.
DR Araport; AT5G46600; -.
DR TAIR; locus:2142290; AT5G46600.
DR eggNOG; KOG4711; Eukaryota.
DR HOGENOM; CLU_020841_1_2_1; -.
DR InParanoid; Q9LS23; -.
DR OMA; TIDIACK; -.
DR OrthoDB; 516124at2759; -.
DR PhylomeDB; Q9LS23; -.
DR PRO; PR:Q9LS23; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LS23; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009705; C:plant-type vacuole membrane; IBA:GO_Central.
DR GO; GO:0034220; P:ion transmembrane transport; IEA:UniProt.
DR GO; GO:0015743; P:malate transport; IEA:InterPro.
DR InterPro; IPR020966; ALMT.
DR Pfam; PF11744; ALMT; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Ion channel; Ion transport; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..539
FT /note="Aluminum-activated malate transporter 13"
FT /id="PRO_0000401472"
FT TRANSMEM 57..77
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 80..100
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 107..127
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 130..150
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 165..185
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 192..212
FT /note="Helical"
FT /evidence="ECO:0000255"
FT VAR_SEQ 327..335
FT /note="TPRSIRVLF -> VIYSTFYLH (in isoform 2)"
FT /evidence="ECO:0000303|Ref.3"
FT /id="VSP_040187"
FT VAR_SEQ 336..539
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.3"
FT /id="VSP_040188"
FT CONFLICT 521
FT /note="A -> P (in Ref. 3; AAU44574)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 539 AA; 60505 MW; DF2CE82262B39DB6 CRC64;
MGYKVEARSM EISMEDEDSR KKRKKGLNLP KKMKKILRNL WNVGKEDPRR VIHALKVGVA
LTLVSLLYLM EPFFEGVGKN ALWAVMTVVV VLEFSAGATL RKGLNRGLGT LIAGSLAFFI
EWVAIHSGKI LGGIFIGTSV FTIGSMITYM RFIPYIKKNY DYGMLVFLLT FNLITVSSYR
VDTVIKIAHE RLYTIGMGIG ICLFMSLLFF PIWSGDDLHK STITKLQGLS RCIEACVSEY
FEEKLKDNET SDSESDDEDL IYNGYNTVLD SKSADEALAM YAKWEPRHTR RCNKFPSQQY
IKVGSVLRKF GYTVVALHGC LQTEIQTPRS IRVLFKDPCV RLAGEICKVL SELSESIQNR
RHCSSEILSD SLEAALKDLN STIKSQPKLF LGSNLHSNIT NKHLNGHVSY YNETNSNGTV
SYHNDNNTNG CVLGETIEEN DTVSPLPLNS VVSLSSLRSV KKSAATGEKR RLRKQLSKIA
VMKSLEFSEA LPFAAFASLL VEMVARLDTV IDEVEELGTI ACFKEYDKTV EVRIENRLI
