ALMT8_ARATH
ID ALMT8_ARATH Reviewed; 488 AA.
AC Q9SRM9;
DT 30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=Aluminum-activated malate transporter 8;
DE Short=AtALMT8;
GN Name=ALMT8; OrderedLocusNames=At3g11680; ORFNames=T19F11.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16740662; DOI=10.1073/pnas.0602868103;
RA Hoekenga O.A., Maron L.G., Pineros M.A., Cancado G.M., Shaff J.,
RA Kobayashi Y., Ryan P.R., Dong B., Delhaize E., Sasaki T., Matsumoto H.,
RA Yamamoto Y., Koyama H., Kochian L.V.;
RT "AtALMT1, which encodes a malate transporter, is identified as one of
RT several genes critical for aluminum tolerance in Arabidopsis.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:9738-9743(2006).
CC -!- FUNCTION: Malate transporter. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the aromatic acid exporter (TC 2.A.85) family.
CC {ECO:0000305}.
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DR EMBL; AC009918; AAF02135.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE75083.1; -; Genomic_DNA.
DR RefSeq; NP_187774.1; NM_112000.1.
DR AlphaFoldDB; Q9SRM9; -.
DR SMR; Q9SRM9; -.
DR STRING; 3702.AT3G11680.1; -.
DR PaxDb; Q9SRM9; -.
DR PRIDE; Q9SRM9; -.
DR EnsemblPlants; AT3G11680.1; AT3G11680.1; AT3G11680.
DR GeneID; 820340; -.
DR Gramene; AT3G11680.1; AT3G11680.1; AT3G11680.
DR KEGG; ath:AT3G11680; -.
DR Araport; AT3G11680; -.
DR TAIR; locus:2098343; AT3G11680.
DR eggNOG; KOG4711; Eukaryota.
DR HOGENOM; CLU_020841_2_2_1; -.
DR InParanoid; Q9SRM9; -.
DR PhylomeDB; Q9SRM9; -.
DR PRO; PR:Q9SRM9; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9SRM9; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009705; C:plant-type vacuole membrane; IBA:GO_Central.
DR GO; GO:0034220; P:ion transmembrane transport; IEA:UniProt.
DR GO; GO:0015743; P:malate transport; IEA:InterPro.
DR InterPro; IPR020966; ALMT.
DR Pfam; PF11744; ALMT; 1.
PE 3: Inferred from homology;
KW Ion channel; Ion transport; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..488
FT /note="Aluminum-activated malate transporter 8"
FT /id="PRO_0000401467"
FT TRANSMEM 45..64
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 66..86
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 101..121
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 127..147
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 160..180
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 189..209
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 488 AA; 54400 MW; 615DAE6E8BB6BE4C CRC64;
MDLNAQEKKA GFFQRLQDFP SKLKDDVTKR VKNVQKFAKD DPRRIIHSMK VGVALTLVSL
LYYVRPLYIS FGVTGMWAIL TVVVVFEFTV GGTLSKGLNR GFATLIAGAL GVGAVHLARF
FGHQGEPIVL GILVFSLGAA ATFSRFFPRI KQRYDYGALI FILTFSFVAI SGYRTDEILI
MAYQRLSTIL IGGTICILVS IFICPVWAGE DLHKMIANNI NKLAKYLEGF EGEYFQPEKI
SKETSSCVRE YKSILTSKST EDSLANLARW EPGHGRFRLR HPWKKYLKIA GLVRQCAVHL
EILNGYVLSN DKAPQEFESK IQEPITTMSR EVGEALKAIA KSIKTMRNDS ACVNAHIDNS
KKAIKNLKIA LKSSYPETYK DLLEIIPGVT MASILIEVVN CVEKIYEAVE EFSGLAHFKE
TLDSKLSAEI GQHQLLHRGC VKPVLDGDNE KEDNSSCHVL ITVHDEGYLP TATAKNVLGA
EKTRVDIV
