ID   ALMT7_ARATH             Reviewed;         506 AA.
AC   Q9XIN1;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Aluminum-activated malate transporter 7;
DE            Short=AtALMT7;
GN   Name=ALMT7; OrderedLocusNames=At2g27240; ORFNames=F12K2.18;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=16740662; DOI=10.1073/pnas.0602868103;
RA   Hoekenga O.A., Maron L.G., Pineros M.A., Cancado G.M., Shaff J.,
RA   Kobayashi Y., Ryan P.R., Dong B., Delhaize E., Sasaki T., Matsumoto H.,
RA   Yamamoto Y., Koyama H., Kochian L.V.;
RT   "AtALMT1, which encodes a malate transporter, is identified as one of
RT   several genes critical for aluminum tolerance in Arabidopsis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:9738-9743(2006).
CC   -!- FUNCTION: Malate transporter. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the aromatic acid exporter (TC 2.A.85) family.
CC       {ECO:0000305}.
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DR   EMBL; AC006233; AAD42005.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC07961.1; -; Genomic_DNA.
DR   PIR; E84670; E84670.
DR   RefSeq; NP_180292.1; NM_128282.1.
DR   AlphaFoldDB; Q9XIN1; -.
DR   SMR; Q9XIN1; -.
DR   STRING; 3702.AT2G27240.1; -.
DR   iPTMnet; Q9XIN1; -.
DR   PaxDb; Q9XIN1; -.
DR   EnsemblPlants; AT2G27240.1; AT2G27240.1; AT2G27240.
DR   GeneID; 817266; -.
DR   Gramene; AT2G27240.1; AT2G27240.1; AT2G27240.
DR   KEGG; ath:AT2G27240; -.
DR   Araport; AT2G27240; -.
DR   TAIR; locus:2039654; AT2G27240.
DR   eggNOG; KOG4711; Eukaryota.
DR   HOGENOM; CLU_020841_2_2_1; -.
DR   InParanoid; Q9XIN1; -.
DR   OMA; VHSSCDS; -.
DR   OrthoDB; 363404at2759; -.
DR   PhylomeDB; Q9XIN1; -.
DR   PRO; PR:Q9XIN1; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q9XIN1; baseline and differential.
DR   Genevisible; Q9XIN1; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0009705; C:plant-type vacuole membrane; IBA:GO_Central.
DR   GO; GO:0034220; P:ion transmembrane transport; IEA:UniProt.
DR   GO; GO:0015743; P:malate transport; IEA:InterPro.
DR   InterPro; IPR020966; ALMT.
DR   Pfam; PF11744; ALMT; 1.
PE   3: Inferred from homology;
KW   Ion channel; Ion transport; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..506
FT                   /note="Aluminum-activated malate transporter 7"
FT                   /id="PRO_0000401466"
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        130..150
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        166..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          461..485
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   506 AA;  56574 MW;  1A367A1049A7B4DA CRC64;
     MEKVREIVRE GRRVAKEDPR RVVHSFKVGL VLALVSSFYY YQPLYDSFGV NAMWAVMTVV
     VVFEFSVGAT LGKGLNRVAA TLFAGGLGIG AHHLASMSGP TGEPILLAVF VFVQAALSTF
     VRFFPRVKAR YDYSLLIFIL TFALISVSGF REEQVVKLTH KRISTVIIGG LSCVIISIFV
     CPVWAGQDLH SLIASNFEKL SFFLLGNSFH YVSSDLNSIT LLRKIKSWRL ADFGDKYCEV
     VENDGAKEVD KRKKDFDNYK SVLNSKSNEE SLANFAKWEP GHGQFRFRHP WKQYLAVGEL
     IRQCAYRIHA LNSYLNADNQ VSVDIKKKLG EPLRRMSLES GKAMKEMSIS LKKMTKPSSS
     DLHVQNAKSA CKSLTNLLNS GILKEVEPLE LVSLLTAISL LIDIINLTEK ILESLHELAT
     AAKFKNKIEH PLFSEKPKAK SFVSVRSIKC HDDHVVIIIE DDGNNDDTSK NDNGSKEVSI
     HEKHEDDDTH VDARCVSCGH TSVCVK