ID   GBB_CRYPA               Reviewed;         359 AA.
AC   O14435;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Guanine nucleotide-binding protein subunit beta;
GN   Name=GB-1;
OS   Cryphonectria parasitica (Chestnut blight fungus) (Endothia parasitica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Diaporthales; Cryphonectriaceae;
OC   Cryphonectria-Endothia species complex; Cryphonectria.
OX   NCBI_TaxID=5116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 38755 / EP155;
RX   PubMed=9353946; DOI=10.1094/mpmi.1997.10.8.984;
RA   Kasahara S., Nuss D.L.;
RT   "Targeted disruption of a fungal G-protein beta subunit gene results in
RT   increased vegetative growth but reduced virulence.";
RL   Mol. Plant Microbe Interact. 10:984-993(1997).
CC   -!- FUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved
CC       as a modulator or transducer in various transmembrane signaling
CC       systems. The beta and gamma chains are required for the GTPase
CC       activity, for replacement of GDP by GTP, and for G protein-effector
CC       interaction.
CC   -!- SUBUNIT: G proteins are composed of 3 units, alpha, beta and gamma.
CC   -!- SIMILARITY: Belongs to the WD repeat G protein beta family.
CC       {ECO:0000305}.
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DR   EMBL; U95139; AAC49838.1; -; Genomic_DNA.
DR   AlphaFoldDB; O14435; -.
DR   SMR; O14435; -.
DR   PRIDE; O14435; -.
DR   OMA; PLDSQWV; -.
DR   PHI-base; PHI:65; -.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR001632; Gprotein_B.
DR   InterPro; IPR016346; Guanine_nucleotide-bd_bsu.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR19850; PTHR19850; 1.
DR   Pfam; PF00400; WD40; 6.
DR   PRINTS; PR00319; GPROTEINB.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 5.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Repeat; Transducer; WD repeat.
FT   CHAIN           1..359
FT                   /note="Guanine nucleotide-binding protein subunit beta"
FT                   /id="PRO_0000127721"
FT   REPEAT          69..99
FT                   /note="WD 1"
FT   REPEAT          111..141
FT                   /note="WD 2"
FT   REPEAT          158..187
FT                   /note="WD 3"
FT   REPEAT          199..230
FT                   /note="WD 4"
FT   REPEAT          242..272
FT                   /note="WD 5"
FT   REPEAT          286..316
FT                   /note="WD 6"
FT   REPEAT          328..358
FT                   /note="WD 7"
FT   REGION          1..36
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..36
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   359 AA;  39843 MW;  E2981F2202BB4A99 CRC64;
     MDSQRPNDVS PEAMQARIQQ ARREAEGLKD RIKRKKDELA DTSLRDVAHR SHEAIPRNQL
     MKTKRTLKGH LAKIYAMHWS TDRRHLVSAS QDGKLIIWDA YTTNKVHAIP LRSSWVMTCA
     YAPSGNYVAC GGLDNICSIY NLNQNRDGPT RVARELSGHA GYLSCCRFIN DRSILTSSGD
     MTCMKWDIET GTKQIEFADH LGDVMSISLN PTNQNTFISG ACDAFAKLWD IRAGKAVQTF
     AGHESDINAI QFFPDGHSFV TGSDDATCRL FDIRADRELN VYGSESILCG ITSVATSVSG
     RLLFAGYDDF ECKVWDVTRG EKVGSLVGHE NRVSCLGVSN DGISLCTGSW DSLLKIWAY