ID   ALL12_ACTDE             Reviewed;          13 AA.
AC   C0HJF9;
DT   08-JUN-2016, integrated into UniProtKB/Swiss-Prot.
DT   08-JUN-2016, sequence version 1.
DT   11-DEC-2019, entry version 4.
DE   RecName: Full=Allergen Act d 12 {ECO:0000303|PubMed:24990823};
DE   AltName: Allergen=Act d 12 {ECO:0000305|PubMed:24990823};
DE   Flags: Fragments;
OS   Actinidia deliciosa (Kiwi).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; Ericales; Actinidiaceae; Actinidia.
OX   NCBI_TaxID=3627 {ECO:0000303|PubMed:24990823};
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, TISSUE SPECIFICITY, ALLERGEN, AND IDENTIFICATION BY MASS
RP   SPECTROMETRY.
RC   TISSUE=Seed {ECO:0000303|PubMed:24990823};
RX   PubMed=24990823; DOI=10.1016/j.jaci.2014.01.035;
RA   Sirvent S., Canto B., Cuesta-Herranz J., Gomez F., Blanca N., Canto G.,
RA   Blanca M., Rodriguez R., Villalba M., Palomares O.;
RT   "Act d 12 and Act d 13: two novel, masked, relevant allergens in kiwifruit
RT   seeds.";
RL   J. Allergy Clin. Immunol. 133:1765-1765(2014).
RN   [2]
RP   MASS SPECTROMETRY.
RC   TISSUE=Seed {ECO:0000303|PubMed:25041438};
RX   PubMed=25041438; DOI=10.1111/all.12486;
RA   Sirvent S., Canto B., Gomez F., Blanca N., Cuesta-Herranz J., Canto G.,
RA   Blanca M., Rodriguez R., Villalba M., Palomares O.;
RT   "Detailed characterization of Act d 12 and Act d 13 from kiwi seeds:
RT   implication in IgE cross-reactivity with peanut and tree nuts.";
RL   Allergy 69:1481-1488(2014).
CC   -!- TISSUE SPECIFICITY: Expressed in seeds but not in fruit pulp.
CC       {ECO:0000269|PubMed:24990823}.
CC   -!- MASS SPECTROMETRY: Mass=50207.3; Method=MALDI; Note=The measured range
CC       is 1-?.; Evidence={ECO:0000269|PubMed:25041438};
CC   -!- MASS SPECTROMETRY: Mass=52280.5; Method=MALDI; Note=The measured range
CC       is 1-?.; Evidence={ECO:0000269|PubMed:25041438};
CC   -!- ALLERGEN: Causes an allergic reaction in human. Binds to IgE.
CC       {ECO:0000269|PubMed:24990823}.
CC   -!- SIMILARITY: Belongs to the 11S seed storage protein (globulins) family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   Allergome; 11947; Act d 12.0101.
DR   Allergome; 9572; Act d 12.
PE   1: Evidence at protein level;
KW   Allergen; Direct protein sequencing.
FT   CHAIN           <1..>13
FT                   /note="Allergen Act d 12"
FT                   /evidence="ECO:0000305"
FT                   /id="PRO_0000436432"
FT   NON_CONS        7..8
FT                   /evidence="ECO:0000303|PubMed:24990823"
FT   NON_TER         1
FT                   /evidence="ECO:0000303|PubMed:24990823"
FT   NON_TER         13
FT                   /evidence="ECO:0000303|PubMed:24990823"
SQ   SEQUENCE   13 AA;  1535 MW;  51DBFF09D1DE6B53 CRC64;
     NRQPSKYGLE ETI