ID   ALGE_PSESM              Reviewed;         493 AA.
AC   Q887Q2;
DT   22-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Alginate production protein AlgE;
DE   Flags: Precursor;
GN   Name=algE; OrderedLocusNames=PSPTO_1239;
OS   Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=223283;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-871 / DC3000;
RX   PubMed=12928499; DOI=10.1073/pnas.1731982100;
RA   Buell C.R., Joardar V., Lindeberg M., Selengut J., Paulsen I.T.,
RA   Gwinn M.L., Dodson R.J., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R.,
RA   Daugherty S.C., Brinkac L.M., Beanan M.J., Haft D.H., Nelson W.C.,
RA   Davidsen T.M., Zafar N., Zhou L., Liu J., Yuan Q., Khouri H.M.,
RA   Fedorova N.B., Tran B., Russell D., Berry K.J., Utterback T.R.,
RA   Van Aken S.E., Feldblyum T.V., D'Ascenzo M., Deng W.-L., Ramos A.R.,
RA   Alfano J.R., Cartinhour S., Chatterjee A.K., Delaney T.P., Lazarowitz S.G.,
RA   Martin G.B., Schneider D.J., Tang X., Bender C.L., White O., Fraser C.M.,
RA   Collmer A.;
RT   "The complete genome sequence of the Arabidopsis and tomato pathogen
RT   Pseudomonas syringae pv. tomato DC3000.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:10181-10186(2003).
CC   -!- FUNCTION: Has non-porin-like, channel-forming properties and probably
CC       functions as an alginate permeability pore. {ECO:0000250}.
CC   -!- PATHWAY: Glycan biosynthesis; alginate biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Peripheral
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AlgE family. {ECO:0000305}.
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DR   EMBL; AE016853; AAO54764.1; -; Genomic_DNA.
DR   RefSeq; NP_791069.1; NC_004578.1.
DR   RefSeq; WP_005615404.1; NC_004578.1.
DR   AlphaFoldDB; Q887Q2; -.
DR   SMR; Q887Q2; -.
DR   STRING; 223283.PSPTO_1239; -.
DR   EnsemblBacteria; AAO54764; AAO54764; PSPTO_1239.
DR   GeneID; 61792619; -.
DR   KEGG; pst:PSPTO_1239; -.
DR   PATRIC; fig|223283.9.peg.1260; -.
DR   eggNOG; ENOG5030R50; Bacteria.
DR   HOGENOM; CLU_564755_0_0_6; -.
DR   OMA; RFSEYRT; -.
DR   OrthoDB; 760987at2; -.
DR   PhylomeDB; Q887Q2; -.
DR   UniPathway; UPA00286; -.
DR   Proteomes; UP000002515; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0042121; P:alginic acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR025388; Alginate_export_dom.
DR   Pfam; PF13372; Alginate_exp; 1.
PE   3: Inferred from homology;
KW   Alginate biosynthesis; Cell outer membrane; Membrane; Reference proteome;
KW   Signal.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..493
FT                   /note="Alginate production protein AlgE"
FT                   /id="PRO_0000020665"
FT   REGION          93..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        93..111
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   493 AA;  54957 MW;  C3A9A34820FB5CA9 CRC64;
     MKLNPLMAAG MGLGFTLFWA CPTLAALTEQ QNFGIEIKAT AQAEDDRDLG TRSGGDVNGV
     GLDLRPWVYG ERGDWSGYAM GQVVTATDTI QTDPLEQSNS DGSGTQTSRG TASEREVEKS
     YAALREFWIG YSGFTPYPGE ILKVGRQRLR NDDGQWHDTN IEAINWNFDT TLLRAELGAA
     QRFSEYRTDL TELAPDDEDR KHLFGSASYQ WTPGHWAGVR AHYSHDDGKL KSQGEQLDDL
     DKTSNGNLTW LGLQADSDAY NYRNTTPLNY WGSLTWLNGT RDEIGVTSAA NDQFFAGEKN
     SRDMNGWATD LGLRLRLDPQ WQVGAAYSRA SKDYIQNGLE SNRSNWTGTR SRIHRFGEAF
     QGEMANVETG SLFASWQMNE EYDASLIYHK FRRVDGNTGI GGSGINAVRE NGDSNTFSSL
     PLEDGRKDLG QEMDLVVTKY FKQGLLPASL SQSFDEPSAL VRLRAGVFKP GDAYHNGVDE
     YMHRAVVDVI WRF