ID   ALGE_PSEPK              Reviewed;         492 AA.
AC   Q88NC8;
DT   22-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Alginate production protein AlgE;
DE   Flags: Precursor;
GN   Name=algE; OrderedLocusNames=PP_1284;
OS   Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950
OS   / KT2440).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=160488;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440;
RX   PubMed=12534463; DOI=10.1046/j.1462-2920.2002.00366.x;
RA   Nelson K.E., Weinel C., Paulsen I.T., Dodson R.J., Hilbert H.,
RA   Martins dos Santos V.A.P., Fouts D.E., Gill S.R., Pop M., Holmes M.,
RA   Brinkac L.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Kolonay J.F.,
RA   Madupu R., Nelson W.C., White O., Peterson J.D., Khouri H.M., Hance I.,
RA   Chris Lee P., Holtzapple E.K., Scanlan D., Tran K., Moazzez A.,
RA   Utterback T.R., Rizzo M., Lee K., Kosack D., Moestl D., Wedler H.,
RA   Lauber J., Stjepandic D., Hoheisel J., Straetz M., Heim S., Kiewitz C.,
RA   Eisen J.A., Timmis K.N., Duesterhoeft A., Tuemmler B., Fraser C.M.;
RT   "Complete genome sequence and comparative analysis of the metabolically
RT   versatile Pseudomonas putida KT2440.";
RL   Environ. Microbiol. 4:799-808(2002).
CC   -!- FUNCTION: Has non-porin-like, channel-forming properties and probably
CC       functions as an alginate permeability pore. {ECO:0000250}.
CC   -!- PATHWAY: Glycan biosynthesis; alginate biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Peripheral
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AlgE family. {ECO:0000305}.
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DR   EMBL; AE015451; AAN66908.1; -; Genomic_DNA.
DR   RefSeq; NP_743444.1; NC_002947.4.
DR   RefSeq; WP_010952413.1; NC_002947.4.
DR   AlphaFoldDB; Q88NC8; -.
DR   SMR; Q88NC8; -.
DR   STRING; 160488.PP_1284; -.
DR   EnsemblBacteria; AAN66908; AAN66908; PP_1284.
DR   KEGG; ppu:PP_1284; -.
DR   PATRIC; fig|160488.4.peg.1361; -.
DR   eggNOG; ENOG5030R50; Bacteria.
DR   HOGENOM; CLU_564755_0_0_6; -.
DR   OMA; RFSEYRT; -.
DR   PhylomeDB; Q88NC8; -.
DR   BioCyc; PPUT160488:G1G01-1371-MON; -.
DR   UniPathway; UPA00286; -.
DR   Proteomes; UP000000556; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0042121; P:alginic acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR025388; Alginate_export_dom.
DR   Pfam; PF13372; Alginate_exp; 1.
PE   3: Inferred from homology;
KW   Alginate biosynthesis; Cell outer membrane; Membrane; Reference proteome;
KW   Signal.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..492
FT                   /note="Alginate production protein AlgE"
FT                   /id="PRO_0000020664"
FT   REGION          89..113
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          323..349
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        332..349
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   492 AA;  54563 MW;  88D20718418EBD21 CRC64;
     MTLNPFVKAG IGLSFALLWS CPTLAEMTAE KNFGLDVKIT GQSEDDRDLG TRSGGDVNGL
     GLDLRPWVYG ERGNWSAYAM GQAVAATDTI ETDTLRQNDD GTSTDTGDDS RQPDKSYLAM
     REFWVGYSGL TAYPGEQLRF GRQRLRSDDG MWRDTNIEAL NWTFDTTLLK ADLGVAQRFS
     EYRTDLTELA PEDKDRTHIY GNVATQWTPG HWVGLRAHHT HDSGSLKNPG ETVDALDKTR
     TGDLTWLGLE ANSDAYNWRN DHTVNYWGSV TWLTGDRDKL STQQVGDDQV ATGKQSGDVN
     AWATDLGIRL RLDPQWQVGA AYARGSGGGG DDGSNNFEQT GLESNRSNFT GTRSRVHRFG
     EAFRGELGNL QAATLFASWQ LRDDYDASLI YHKFWRVDGN QNIGSSGINA VVDDNGVNRQ
     LVDGEKDLGQ EMDVVVTKYF KQGLLPASMS QAIDEPSALV RLRAGVFKPG DAYGKETDSY
     MHRAFVDVIW RF