ID   ALGE_AZOVI              Reviewed;         484 AA.
AC   Q44497; P94201;
DT   22-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Alginate production protein AlgE;
DE   Flags: Precursor;
GN   Name=algE; Synonyms=algJ;
OS   Azotobacter vinelandii.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Azotobacter.
OX   NCBI_TaxID=354;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=E;
RX   PubMed=8936313; DOI=10.1099/00221287-142-4-873;
RA   Rehm B.H.A.;
RT   "The Azotobacter vinelandii gene algJ encodes an outer-membrane protein
RT   presumably involved in export of alginate.";
RL   Microbiology 142:873-880(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-128.
RC   STRAIN=ATCC 9046;
RX   PubMed=9368366; DOI=10.1111/j.1574-6968.1997.tb12712.x;
RA   Mejia-Ruiz H., Moreno S., Guzman J., Najera R., Leon R., Soberon-Chavez G.,
RA   Espin G.;
RT   "Isolation and characterization of an Azotobacter vinelandii algK mutant.";
RL   FEMS Microbiol. Lett. 156:101-106(1997).
CC   -!- FUNCTION: Has non-porin-like, channel-forming properties and probably
CC       functions as an alginate permeability pore.
CC   -!- PATHWAY: Glycan biosynthesis; alginate biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Peripheral membrane protein.
CC   -!- SIMILARITY: Belongs to the AlgE family. {ECO:0000305}.
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DR   EMBL; X86533; CAA60245.1; -; Genomic_DNA.
DR   EMBL; X98863; CAA67371.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q44497; -.
DR   SMR; Q44497; -.
DR   TCDB; 1.B.13.1.2; the alginate export porin (aep) family.
DR   PRIDE; Q44497; -.
DR   UniPathway; UPA00286; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0042121; P:alginic acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR025388; Alginate_export_dom.
DR   Pfam; PF13372; Alginate_exp; 1.
PE   3: Inferred from homology;
KW   Alginate biosynthesis; Cell outer membrane; Membrane; Signal.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..484
FT                   /note="Alginate production protein AlgE"
FT                   /id="PRO_0000020662"
FT   REGION          93..118
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   484 AA;  54611 MW;  0A4CCF18C928DBD3 CRC64;
     MSRKQRISAG LGLGASLLCC NPLFAGPVGP DRNFGMEVKV TAQSEDDRDL DTRSGGDAEG
     IALDLRPWVY GQRGNWGAMV MLQAVAATDI IETDPTDPNE EPGGDPANGF SRDSSRDPDK
     SYLALREFEL GTIGRQRIRS LTNEGTWWDI HMESVNWTMD TSLLRAQAGV AKRFDEYRTD
     LDNLSAEDKD RTHVFGGLDY QWRQGHWAGF KVHHTSDDGD LPDSQMDVYE DRQSKSYTGD
     LTWLSVHLDR DFFNPRSTLP INYWGEFTWL TGEMDRSHFA SDGSADHYKD VDVDAWAVDL
     GLRWNISDRW NVGAAYARGQ AGEGDDESEQ FMQTGLQSNR STFTGLQTRI HRFGEASRGE
     LTNLQVGTLF TSWKPREDLE TSLIYHKFWR VDDDEDLGQN GISPIEKDGK PALKAGEKDL
     GQEVDLIITR YFNQGMLPAN WGGELDEQSA LIRLRSGLFF PSNAYASKGD SKMHRVFVDM
     IWRF