ID   GALA_AMICA              Reviewed;          29 AA.
AC   P47214;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Galanin;
GN   Name=gal;
OS   Amia calva (Bowfin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Holostei; Amiiformes; Amiidae; Amia.
OX   NCBI_TaxID=7924;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT ALA-29.
RC   TISSUE=Stomach;
RX   PubMed=7527531; DOI=10.1016/0196-9781(94)90060-4;
RA   Wang Y., Conlon J.M.;
RT   "Purification and characterization of galanin from the phylogenetically
RT   ancient fish, the bowfin (Amia calva) and dogfish (Scyliorhinus
RT   canicula).";
RL   Peptides 15:981-986(1994).
CC   -!- FUNCTION: Contracts smooth muscle of the gastrointestinal and
CC       genitourinary tract, regulates growth hormone release, modulates
CC       insulin release, and may be involved in the control of adrenal
CC       secretion.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the galanin family. {ECO:0000305}.
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DR   AlphaFoldDB; P47214; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR008174; Galanin.
DR   InterPro; IPR008175; Galanin_pre.
DR   PANTHER; PTHR16839; PTHR16839; 1.
DR   Pfam; PF01296; Galanin; 1.
DR   PRINTS; PR00273; GALANIN.
DR   PROSITE; PS00861; GALANIN; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Hormone; Neuropeptide; Secreted.
FT   PEPTIDE         1..29
FT                   /note="Galanin"
FT                   /id="PRO_0000043875"
FT   MOD_RES         29
FT                   /note="Alanine amide"
FT                   /evidence="ECO:0000269|PubMed:7527531"
SQ   SEQUENCE   29 AA;  3114 MW;  7518719B2D271627 CRC64;
     GWTLNSAGYL LGPHAVDNHR SLNDKHGLA