ID   FTSE_HAEIN              Reviewed;         218 AA.
AC   P44871;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 126.
DE   RecName: Full=Cell division ATP-binding protein FtsE;
GN   Name=ftsE; OrderedLocusNames=HI_0769;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Part of the ABC transporter FtsEX involved in cellular
CC       division. Important for assembly or stability of the septal ring.
CC       {ECO:0000250|UniProtKB:P0A9R7}.
CC   -!- SUBUNIT: Homodimer. Forms a membrane-associated complex with FtsX.
CC       {ECO:0000250|UniProtKB:P0A9R7}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000250|UniProtKB:P0A9R7}; Peripheral membrane protein
CC       {ECO:0000250|UniProtKB:P0A9R7}; Cytoplasmic side
CC       {ECO:0000250|UniProtKB:P0A9R7}. Note=Associated with the membrane
CC       through an interaction with FtsX. {ECO:0000250|UniProtKB:P0A9R7}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L42023; AAC22427.1; -; Genomic_DNA.
DR   PIR; H64091; H64091.
DR   RefSeq; NP_438928.1; NC_000907.1.
DR   RefSeq; WP_005632750.1; NC_000907.1.
DR   AlphaFoldDB; P44871; -.
DR   SMR; P44871; -.
DR   STRING; 71421.HI_0769; -.
DR   EnsemblBacteria; AAC22427; AAC22427; HI_0769.
DR   KEGG; hin:HI_0769; -.
DR   PATRIC; fig|71421.8.peg.808; -.
DR   eggNOG; COG2884; Bacteria.
DR   HOGENOM; CLU_000604_1_22_6; -.
DR   OMA; CHNLETA; -.
DR   PhylomeDB; P44871; -.
DR   BioCyc; HINF71421:G1GJ1-809-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR005286; Cell_div_FtsE_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02673; FtsE; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell cycle; Cell division; Cell inner membrane; Cell membrane;
KW   Membrane; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..218
FT                   /note="Cell division ATP-binding protein FtsE"
FT                   /id="PRO_0000092331"
FT   DOMAIN          2..218
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         36..43
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   218 AA;  24349 MW;  6E3DFE39C03F33EB CRC64;
     MIKFSNVSKA YHGATQPALQ GLNFHLPVGS MTYLVGHSGA GKSTLLKLIM GMEKANAGQI
     WFNGHDITRL SKYEIPFLRR QIGMVHQDYR LLTDRTVVEN VALPLIIAGM HPKDANTRAM
     ASLDRVGLRN KAHYLPPQIS GGEQQRVDIA RAIVHKPQLL LADEPTGNLD DELSLGIFNL
     FEEFNRLGMT VLIATHDINL IQQKPKPCLV LEQGYLRY