FTSB_VIBCH
ID FTSB_VIBCH Reviewed; 94 AA.
AC Q9KUJ3;
DT 15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT 25-JUL-2003, sequence version 2.
DT 25-MAY-2022, entry version 103.
DE RecName: Full=Cell division protein FtsB {ECO:0000255|HAMAP-Rule:MF_00599};
GN Name=ftsB {ECO:0000255|HAMAP-Rule:MF_00599}; OrderedLocusNames=VC_0527;
OS Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=243277;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX PubMed=10952301; DOI=10.1038/35020000;
RA Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT cholerae.";
RL Nature 406:477-483(2000).
RN [2]
RP CHARACTERIZATION.
RC STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX PubMed=11972052; DOI=10.1073/pnas.092128499;
RA Buddelmeijer N., Judson N., Boyd D., Mekalanos J.J., Beckwith J.;
RT "YgbQ, a cell division protein in Escherichia coli and Vibrio cholerae,
RT localizes in codependent fashion with FtsL to the division site.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:6316-6321(2002).
CC -!- FUNCTION: Essential cell division protein. May link together the
CC upstream cell division proteins, which are predominantly cytoplasmic,
CC with the downstream cell division proteins, which are predominantly
CC periplasmic. {ECO:0000255|HAMAP-Rule:MF_00599}.
CC -!- SUBUNIT: Part of a complex composed of FtsB, FtsL and FtsQ.
CC {ECO:0000255|HAMAP-Rule:MF_00599}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00599}; Single-pass type II membrane protein
CC {ECO:0000255|HAMAP-Rule:MF_00599}. Note=Localizes to the division
CC septum. {ECO:0000255|HAMAP-Rule:MF_00599}.
CC -!- SIMILARITY: Belongs to the FtsB family. {ECO:0000255|HAMAP-
CC Rule:MF_00599}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF93695.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AE003852; AAF93695.1; ALT_INIT; Genomic_DNA.
DR PIR; B82311; B82311.
DR RefSeq; NP_230178.1; NC_002505.1.
DR RefSeq; WP_001263189.1; NZ_LT906614.1.
DR AlphaFoldDB; Q9KUJ3; -.
DR SMR; Q9KUJ3; -.
DR STRING; 243277.VC_0527; -.
DR DNASU; 2615818; -.
DR EnsemblBacteria; AAF93695; AAF93695; VC_0527.
DR GeneID; 57739245; -.
DR GeneID; 66938790; -.
DR KEGG; vch:VC_0527; -.
DR PATRIC; fig|243277.26.peg.503; -.
DR eggNOG; COG2919; Bacteria.
DR HOGENOM; CLU_134863_5_2_6; -.
DR OMA; YELGMVK; -.
DR Proteomes; UP000000584; Chromosome 1.
DR GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR GO; GO:0030428; C:cell septum; IBA:GO_Central.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0043093; P:FtsZ-dependent cytokinesis; IBA:GO_Central.
DR HAMAP; MF_00599; FtsB; 1.
DR InterPro; IPR023081; Cell_div_FtsB.
DR InterPro; IPR007060; FtsL/DivIC.
DR PANTHER; PTHR37485; PTHR37485; 1.
DR Pfam; PF04977; DivIC; 1.
PE 1: Evidence at protein level;
KW Cell cycle; Cell division; Cell inner membrane; Cell membrane; Coiled coil;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..94
FT /note="Cell division protein FtsB"
FT /id="PRO_0000214457"
FT TOPO_DOM 1..3
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00599"
FT TRANSMEM 4..21
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00599"
FT TOPO_DOM 22..94
FT /note="Periplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00599"
FT COILED 33..76
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00599"
SQ SEQUENCE 94 AA; 10987 MW; CE7DF6651369821D CRC64;
MRVFALTLSL LLVWLLYTLM WGKNGVMDFR AVQAEIEVQQ QVNANLHLRN QEMFAEIDDL
RQGLDAIEER ARNELGMVKD GETFYRIIGE ESRQ
