ID   FRSA_SALA4              Reviewed;         414 AA.
AC   B5EWK1;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   14-OCT-2008, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Esterase FrsA {ECO:0000255|HAMAP-Rule:MF_01063};
DE            EC=3.1.1.1 {ECO:0000255|HAMAP-Rule:MF_01063};
GN   Name=frsA {ECO:0000255|HAMAP-Rule:MF_01063}; OrderedLocusNames=SeAg_B0352;
OS   Salmonella agona (strain SL483).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=454166;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SL483;
RX   PubMed=21602358; DOI=10.1128/jb.00297-11;
RA   Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G.,
RA   Leclerc J.E., Ravel J., Cebula T.A.;
RT   "Comparative genomics of 28 Salmonella enterica isolates: evidence for
RT   CRISPR-mediated adaptive sublineage evolution.";
RL   J. Bacteriol. 193:3556-3568(2011).
CC   -!- FUNCTION: Catalyzes the hydrolysis of esters. {ECO:0000255|HAMAP-
CC       Rule:MF_01063}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a carboxylic ester + H2O = a carboxylate + an alcohol + H(+);
CC         Xref=Rhea:RHEA:21164, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:29067, ChEBI:CHEBI:30879, ChEBI:CHEBI:33308; EC=3.1.1.1;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01063};
CC   -!- SIMILARITY: Belongs to the FrsA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01063}.
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DR   EMBL; CP001138; ACH50525.1; -; Genomic_DNA.
DR   RefSeq; WP_000189586.1; NC_011149.1.
DR   AlphaFoldDB; B5EWK1; -.
DR   SMR; B5EWK1; -.
DR   ESTHER; salty-yafa; Duf_1100-R.
DR   PRIDE; B5EWK1; -.
DR   EnsemblBacteria; ACH50525; ACH50525; SeAg_B0352.
DR   KEGG; sea:SeAg_B0352; -.
DR   HOGENOM; CLU_036819_0_0_6; -.
DR   OMA; NIPWVDH; -.
DR   Proteomes; UP000008819; Chromosome.
DR   GO; GO:0080030; F:methyl indole-3-acetate esterase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   HAMAP; MF_01063; FrsA; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR043423; FrsA.
DR   InterPro; IPR010520; FrsA-like.
DR   Pfam; PF06500; FrsA-like; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Serine esterase.
FT   CHAIN           1..414
FT                   /note="Esterase FrsA"
FT                   /id="PRO_1000136520"
SQ   SEQUENCE   414 AA;  47141 MW;  B0B2843A26B27F23 CRC64;
     MTQANLSETL FKPRFKHTET STLVRRFNRG SQPPMQSALD GKNVPHWYRM INRLMWIWRG
     VDPREILDVQ ARIVMSDAER TDDDLYDTVI GYRGGNWIYE WAKQAMDWQQ KACQEQDAMR
     SGRYWLHAST LYNIAAYPHL KGDELAEQAQ ALANRAYEEA AQRLPGSLRE MEFAVPGGSP
     VTAFLHMPKG DGPFPTVLMC GGLDAMQTDY YTLYERYFAP RGIAMLTLDM PSVGFSSKWK
     LTQDSSLLHQ HVLKALPNVP WVDHTRVAAF GFRFGANVAV RLAYLEAPRL KAVACLGPVV
     HALLSDPQRQ STVPEMYLDV LASRLGMHDA SDEALRVELN RYSLKVQGLL GRRCPTPMLS
     GFWKNDPFSP EEESRLITTS SSDGKLIEIP FNPVYRNFDH ALQEITDWIN HRLC