FRL5_ARATH
ID FRL5_ARATH Reviewed; 948 AA.
AC Q5XV31; O04649;
DT 16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 25-MAY-2022, entry version 84.
DE RecName: Full=FRIGIDA-like protein 5;
GN Name=FRL5; OrderedLocusNames=At5g27230; ORFNames=A_TM021B04.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY.
RX PubMed=14973192; DOI=10.1073/pnas.0306778101;
RA Michaels S.D., Bezerra I.C., Amasino R.M.;
RT "FRIGIDA-related genes are required for the winter-annual habit in
RT Arabidopsis.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:3281-3285(2004).
RN [5]
RP GENE FAMILY, NOMENCLATURE, AND TISSUE SPECIFICITY.
RX PubMed=20405310; DOI=10.1007/s11103-010-9635-2;
RA Risk J.M., Laurie R.E., Macknight R.C., Day C.L.;
RT "FRIGIDA and related proteins have a conserved central domain and family
RT specific N- and C- terminal regions that are functionally important.";
RL Plant Mol. Biol. 73:493-505(2010).
CC -!- TISSUE SPECIFICITY: Expressed at low levels during seed development.
CC {ECO:0000269|PubMed:20405310}.
CC -!- SIMILARITY: Belongs to the Frigida family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB61078.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AF007271; AAB61078.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED93660.1; -; Genomic_DNA.
DR EMBL; AY735691; AAU44561.1; -; mRNA.
DR PIR; T01798; T01798.
DR RefSeq; NP_198075.1; NM_122605.2.
DR AlphaFoldDB; Q5XV31; -.
DR SMR; Q5XV31; -.
DR STRING; 3702.AT5G27230.1; -.
DR PaxDb; Q5XV31; -.
DR PRIDE; Q5XV31; -.
DR ProteomicsDB; 228951; -.
DR EnsemblPlants; AT5G27230.1; AT5G27230.1; AT5G27230.
DR GeneID; 832781; -.
DR Gramene; AT5G27230.1; AT5G27230.1; AT5G27230.
DR KEGG; ath:AT5G27230; -.
DR Araport; AT5G27230; -.
DR TAIR; locus:2181251; AT5G27230.
DR eggNOG; ENOG502SIE9; Eukaryota.
DR HOGENOM; CLU_316033_0_0_1; -.
DR InParanoid; Q5XV31; -.
DR OMA; NAFRCTS; -.
DR OrthoDB; 306768at2759; -.
DR PhylomeDB; Q5XV31; -.
DR PRO; PR:Q5XV31; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q5XV31; baseline and differential.
DR Genevisible; Q5XV31; AT.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR InterPro; IPR012474; Frigida.
DR Pfam; PF07899; Frigida; 2.
PE 2: Evidence at transcript level;
KW Coiled coil; Developmental protein; Differentiation; Flowering;
KW Reference proteome.
FT CHAIN 1..948
FT /note="FRIGIDA-like protein 5"
FT /id="PRO_0000423745"
FT REGION 447..500
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 518..538
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 804..894
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 47..164
FT /evidence="ECO:0000255"
FT COMPBIAS 464..491
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 804..832
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 843..861
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 872..894
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 948 AA; 106573 MW; 69D99EE6FBF5A4A6 CRC64;
MEKVTSGLEL VDISKRNFRK TLESLQEGAH SLLLLTIQWK EIESYFDSTR SVLEERAKEL
EALEESIKVK ALELEKKEKE LCLIDESMKA KQSEFEKKEK DFDLEQKAEV EKRKREVEQL
EKFTTRMESV ERVSDEKLME LGLRATELEL KMEEVEKHRE RIVAGDKLRG EFEPLVSLLA
KNMGLSVTMP VKCSTLYLNE NADEMVKKNT ALARMVPYLD PAKVVLDAIE GSFKEYWKKD
LGEADDRVVN SWIVLLENLI KMNLKITPQV KQEATPLGIA WLGKAKANMK NDPPQVFGCA
LFLAAYGLGS LTTHGVLLTL VERFLLYDHA PKLFRLLGLE EKVSGAVETL KKKEEYLATL
KFICEFRLYK LCPGGRPGEL LIEFFDSSDK AARVIAGTGT SMEAQKARRE KKKADAAMAI
KYIKEAKAET MFPAKILKRL AVVKNDESAQ RAMEPVQKSY EKRQSTTKGV EKSEAKSSIP
YEQKHVIKRP RLTEPTAPSQ NLTVKQPEVV CVPTGKQVKE SGADHQPDTI ATHPSGTETK
LNILSGSIKA DMLRELVEKQ PLKESEDLSN ALKCTPDPAK LFLDTSMALC PTNTEGGYEF
KMLITSASCS LLLNQLKKLL PKIGHPVKGD AKKLAVYWKD KIAKSKRDQL EVICFLQFLG
IFGIVSEFKA DDLLGLLDNS YWQTVSPDLC QFLGLDDAIP GFIQNLIKTG HRIKAIDYIY
SFGMVHRFQP VSAIINDSLR ITKESAEKSY REAKNESTTQ VAAIDRQVRA LRAAIKCISC
HKLESEFQLG DLEEQIKSLL KLRRNTSNGS GSGSASSKPD STIKQSQTAK PPTVAEVAPV
TSNIPLEPST EAASSSASKP FSKKNKRGKK RSMSGNNQSS GHIASHTSNH YPSHDYSLNQ
RLTWPVDNYD RGFTGFPNPD YNNNQWGQPE GPQFYHLYQP LDPRYRNY
