ID   FLID_ECO57              Reviewed;         465 AA.
AC   P58297;
DT   26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Flagellar hook-associated protein 2;
DE            Short=HAP2;
DE   AltName: Full=Filament cap protein;
DE   AltName: Full=Flagellar cap protein;
GN   Name=fliD; Synonyms=flaV, flbC; OrderedLocusNames=Z3014, ECs2663;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Required for the morphogenesis and for the elongation of the
CC       flagellar filament by facilitating polymerization of the flagellin
CC       monomers at the tip of growing filament. Forms a capping structure,
CC       which prevents flagellin subunits (transported through the central
CC       channel of the flagellum) from leaking out without polymerization at
CC       the distal end (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homopentamer. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Secreted. Bacterial flagellum.
CC   -!- SIMILARITY: Belongs to the FliD family. {ECO:0000305}.
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DR   EMBL; AE005174; AAG56939.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB36086.1; -; Genomic_DNA.
DR   PIR; G85809; G85809.
DR   PIR; G90961; G90961.
DR   RefSeq; NP_310690.1; NC_002695.1.
DR   RefSeq; WP_000146755.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P58297; -.
DR   SMR; P58297; -.
DR   STRING; 155864.EDL933_2932; -.
DR   EnsemblBacteria; AAG56939; AAG56939; Z3014.
DR   EnsemblBacteria; BAB36086; BAB36086; ECs_2663.
DR   GeneID; 913755; -.
DR   KEGG; ece:Z3014; -.
DR   KEGG; ecs:ECs_2663; -.
DR   PATRIC; fig|386585.9.peg.2791; -.
DR   eggNOG; COG1345; Bacteria.
DR   HOGENOM; CLU_015182_8_1_6; -.
DR   OMA; TLEWQRD; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR   GO; GO:0009424; C:bacterial-type flagellum hook; IEA:InterPro.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   InterPro; IPR040026; FliD.
DR   InterPro; IPR010809; FliD_C.
DR   InterPro; IPR003481; FliD_N.
DR   PANTHER; PTHR30288; PTHR30288; 1.
DR   Pfam; PF07195; FliD_C; 1.
DR   Pfam; PF02465; FliD_N; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum; Coiled coil; Reference proteome; Secreted.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..465
FT                   /note="Flagellar hook-associated protein 2"
FT                   /id="PRO_0000177018"
FT   COILED          408..436
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   465 AA;  48153 MW;  1B286643E6483851 CRC64;
     MASISSLGVG SGLDLSSILD SLTAAQKATL TPISNQQSSF TAKLSAYGTL KSALTTFQTA
     NTALSKADLF SATSSTTAFS ATTAGNAIAG KYTISVTHLA QAQTLTTRTT RDDTKTAIAT
     SDSKLTIQQG GDKDPITIDI SAANSSLSGI RDAINNAKAG VSASIINVGN GDYRLSVTSN
     DTGLDNAMTL SVSGDDALQS FMGYDASASS NGMEVSVAAQ NAQLTVNNVA IENSSNTISD
     ALENITLNLN DVTTGNQTLT ITQDTSKAQT AIKDWVNAYN SLIDTFSSLT KYTAVDAGAD
     SQSSSNGALL GDSTLRTIQT QLKSMLSNTV SSSSYKTLAQ IGITTDPSDG KLELDADKLT
     AALKKDASGV GALIVGDGKK TGITTTIGSN LTSWLSTTGI IKAATDGVSK TLNKLTKDYN
     AASDRIDAQV ARYKEQFTQL DVLMTSLNST SSYLTQQFEN NSNSK