FEZ_ARATH
ID FEZ_ARATH Reviewed; 418 AA.
AC Q9ZVH0; F4HPE2;
DT 19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Protein FEZ;
DE AltName: Full=NAC domain-containing protein 9;
DE Short=ANAC009;
GN Name=FEZ; Synonyms=NAC009; OrderedLocusNames=At1g26870; ORFNames=T2P11.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15029955; DOI=10.1093/dnares/10.6.239;
RA Ooka H., Satoh K., Doi K., Nagata T., Otomo Y., Murakami K., Matsubara K.,
RA Osato N., Kawai J., Carninci P., Hayashizaki Y., Suzuki K., Kojima K.,
RA Takahara Y., Yamamoto K., Kikuchi S.;
RT "Comprehensive analysis of NAC family genes in Oryza sativa and Arabidopsis
RT thaliana.";
RL DNA Res. 10:239-247(2003).
RN [4]
RP FUNCTION, TISSUE SPECIFICITY, SUBCELLULAR LOCATION, INDUCTION BY SMB,
RP DEVELOPMENTAL STAGE, AND DISRUPTION PHENOTYPE.
RX PubMed=19081078; DOI=10.1016/j.devcel.2008.09.019;
RA Willemsen V., Bauch M., Bennett T., Campilho A., Wolkenfelt H., Xu J.,
RA Haseloff J., Scheres B.;
RT "The NAC domain transcription factors FEZ and SOMBRERO control the
RT orientation of cell division plane in Arabidopsis root stem cells.";
RL Dev. Cell 15:913-922(2008).
CC -!- FUNCTION: Promotes periclinal root capforming cell divisions. Activates
CC expression of its negative regulator SMB in a feedback loop for
CC controlled switches in cell division plane.
CC {ECO:0000269|PubMed:19081078}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00353,
CC ECO:0000269|PubMed:19081078}.
CC -!- TISSUE SPECIFICITY: Expressed in root cap stem cells and their
CC immediate daughters. {ECO:0000269|PubMed:19081078}.
CC -!- DEVELOPMENTAL STAGE: First expressed at globular stage onward in the
CC COL progenitors after the first division of the hypophyseal cell. Later
CC observed in these cells and their descendants, mostly in direct
CC daughter cells. Also detected in the Epi/LRC stem cells and daughters,
CC and is retained in maturing LRC layers. Present in elongated stem cells
CC that are about to divide. {ECO:0000269|PubMed:19081078}.
CC -!- INDUCTION: Repressed by SMB in oriented-divised root cap stem cells.
CC {ECO:0000269|PubMed:19081078}.
CC -!- DOMAIN: The NAC domain includes a DNA-binding domain and a dimerization
CC domain.
CC -!- DISRUPTION PHENOTYPE: Fewer root cap layers; reduced number of
CC columella (COL) and lateral root cap (LRC) cell layers from late
CC embryogenesis due to impaired periclinal divisions in epidermal
CC (Epi)/LRC and COL stem cells. {ECO:0000269|PubMed:19081078}.
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DR EMBL; AC005508; AAD14493.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30752.2; -; Genomic_DNA.
DR PIR; E86395; E86395.
DR RefSeq; NP_174009.2; NM_102451.2.
DR AlphaFoldDB; Q9ZVH0; -.
DR SMR; Q9ZVH0; -.
DR STRING; 3702.AT1G26870.1; -.
DR PaxDb; Q9ZVH0; -.
DR PRIDE; Q9ZVH0; -.
DR ProteomicsDB; 230593; -.
DR EnsemblPlants; AT1G26870.1; AT1G26870.1; AT1G26870.
DR GeneID; 837796; -.
DR Gramene; AT1G26870.1; AT1G26870.1; AT1G26870.
DR KEGG; ath:AT1G26870; -.
DR Araport; AT1G26870; -.
DR TAIR; locus:2202820; AT1G26870.
DR eggNOG; ENOG502QRAX; Eukaryota.
DR HOGENOM; CLU_035664_8_4_1; -.
DR InParanoid; Q9ZVH0; -.
DR OMA; HENMNTP; -.
DR OrthoDB; 990948at2759; -.
DR PhylomeDB; Q9ZVH0; -.
DR PRO; PR:Q9ZVH0; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9ZVH0; baseline and differential.
DR Genevisible; Q9ZVH0; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0045770; P:positive regulation of asymmetric cell division; IMP:TAIR.
DR GO; GO:0009733; P:response to auxin; IEP:TAIR.
DR GO; GO:0048829; P:root cap development; IMP:TAIR.
DR GO; GO:0048103; P:somatic stem cell division; IMP:TAIR.
DR Gene3D; 2.170.150.80; -; 1.
DR InterPro; IPR003441; NAC-dom.
DR InterPro; IPR036093; NAC_dom_sf.
DR Pfam; PF02365; NAM; 1.
DR SUPFAM; SSF101941; SSF101941; 1.
DR PROSITE; PS51005; NAC; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..418
FT /note="Protein FEZ"
FT /id="PRO_0000132307"
FT DOMAIN 16..175
FT /note="NAC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
FT DNA_BIND 115..181
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00353"
SQ SEQUENCE 418 AA; 47805 MW; 2E9792B6DB0CD18E CRC64;
MGDRNNDGDQ KMEDVLLPGF RFHPTDEELV SFYLKRKVQH NPLSIELIRQ LDIYKYDPWD
LPKFAMTGEK EWYFYCPRDR KYRNSSRPNR VTGAGFWKAT GTDRPIYSSE GNKCIGLKKS
LVFYKGRAAK GVKTDWMMHE FRLPSLSEPS PPSKRFFDSP VSPNDSWAIC RIFKKTNTTT
LRALSHSFVS SLPPETSTDT MSNQKQSNTY HFSSDKILKP SSHFQFHHEN MNTPKTSNST
TPSVPTISPF SYLDFTSYDK PTNVFNPVSC LDQQYLTNLF LATQETQPQF PRLPSSNEIP
SFLLNTSSDS TFLGEFTSHI DLSAVLAQEQ CPPLVSLPQE YQETGFEGNG IMKNMRGSNE
DHLGDHCDTL RFDDFTSTIN ENHRHHQDLK QNMTLLESYY SSLSSINSDL PACFSSTT
