ID   AJSP1_TRINI             Reviewed;         624 AA.
AC   P22327;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1991, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Acidic juvenile hormone-suppressible protein 1;
DE            Short=AJHSP1;
DE   Flags: Precursor;
GN   Name=AJSP-1;
OS   Trichoplusia ni (Cabbage looper).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC   Noctuidae; Plusiinae; Trichoplusia.
OX   NCBI_TaxID=7111;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND PROTEIN SEQUENCE OF 19-40.
RC   TISSUE=Hemolymph;
RX   PubMed=2341396; DOI=10.1016/s0021-9258(19)38929-x;
RA   Jones G., Brown N., Manczak M., Hiremath S., Kafatos F.C.;
RT   "Molecular cloning, regulation, and complete sequence of a hemocyanin-
RT   related, juvenile hormone-suppressible protein from insect hemolymph.";
RL   J. Biol. Chem. 265:8596-8602(1990).
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space.
CC   -!- DEVELOPMENTAL STAGE: Associated with larval metamorphosis.
CC   -!- INDUCTION: Suppressed by juvenile hormone.
CC   -!- SIMILARITY: Belongs to the hemocyanin family. {ECO:0000305}.
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DR   EMBL; M57443; AAA27884.1; ALT_SEQ; mRNA.
DR   PIR; A36269; A36269.
DR   AlphaFoldDB; P22327; -.
DR   SMR; P22327; -.
DR   Proteomes; UP000322000; Genome assembly.
DR   GO; GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell.
DR   GO; GO:0045735; F:nutrient reservoir activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1280.10; -; 1.
DR   Gene3D; 1.20.1370.10; -; 1.
DR   Gene3D; 2.60.40.1520; -; 1.
DR   InterPro; IPR008922; Di-copper_centre_dom_sf.
DR   InterPro; IPR013788; Hemocyanin/hexamerin.
DR   InterPro; IPR000896; Hemocyanin/hexamerin_mid_dom.
DR   InterPro; IPR005203; Hemocyanin_C.
DR   InterPro; IPR037020; Hemocyanin_C_sf.
DR   InterPro; IPR005204; Hemocyanin_N.
DR   InterPro; IPR036697; Hemocyanin_N_sf.
DR   InterPro; IPR014756; Ig_E-set.
DR   PANTHER; PTHR11511; PTHR11511; 1.
DR   Pfam; PF03723; Hemocyanin_C; 1.
DR   Pfam; PF00372; Hemocyanin_M; 1.
DR   Pfam; PF03722; Hemocyanin_N; 1.
DR   SUPFAM; SSF48050; SSF48050; 1.
DR   SUPFAM; SSF48056; SSF48056; 1.
DR   SUPFAM; SSF81296; SSF81296; 1.
DR   PROSITE; PS00210; HEMOCYANIN_2; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Glycoprotein; Reference proteome; Secreted;
KW   Signal; Storage protein.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000269|PubMed:2341396"
FT   CHAIN           19..624
FT                   /note="Acidic juvenile hormone-suppressible protein 1"
FT                   /id="PRO_0000013342"
FT   CARBOHYD        75
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        478
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   624 AA;  72768 MW;  FEF78CDDEB4FB4F1 CRC64;
     MARLVLCALA LLVAGGLADP VRNNVPQKPA DPVFAKRQMD LMTLFFHVLE PNYIEANKVI
     VNTWSLEKNI EHFSNVTAVT TYIKMLENQC CVPRAVPFSI LEDEHKFEVV TLFNVLHSAK
     DYDTFYKTAV YVRDRVNPDL FSYVLSAVIV NRPDTKGIYI PRVFEIFPSY FNNGEIMTTA
     ARINTHGDRL VDFYPSTYKW DKNVVIRWNP HLALLQQPEH TYSLLHSRLQ PQLILLQRSL
     SLPGWLQTEA LPVNQHRRGE WFWFLHKQLI ARYYMERLSN GLGEIPELGH ETVKDGTTRS
     FGTTMEFSSP VRPNNFNLDQ PEFVNEVEQI YDYERRVRDA IDQGYVLNHL GERIDISAPE
     AIEILGRVIE ANVDSPNVQY YKDFISVWKK VLGNSLVHEH QYFHHYIPLV VPSVLEHYQT
     ALRDPAFYMI WKRVLGLFQQ WQEKLPHYKP EELAMPQVAI EKVDVDKLVT YFEYSYMNVT
     SGLPMNVEEA KELYDQVSVL VQHPRLNHKK FQVRVNVKTE VAKTVLVKFF LAPKYDSHGH
     EIPLHVNSYN FMQLDEFVYD LPQGESVITR DSVETTGNEW TTSYQVWDQA EKASREKHLS
     AKNMYFQDVL IYHKHTLNPC SHVE