FDM5_ARATH
ID FDM5_ARATH Reviewed; 634 AA.
AC Q9SAI1; B9DHL1; Q0WUU8;
DT 29-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Factor of DNA methylation 5 {ECO:0000303|PubMed:22302148};
GN Name=FDM5 {ECO:0000303|PubMed:22302148};
GN OrderedLocusNames=At1g80790 {ECO:0000312|Araport:AT1G80790};
GN ORFNames=F23A5.14 {ECO:0000312|EMBL:AAF14667.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-439.
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 83-634.
RC STRAIN=cv. Columbia;
RX PubMed=19423640; DOI=10.1093/dnares/dsp009;
RA Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M.,
RA Shinozaki K.;
RT "Analysis of multiple occurrences of alternative splicing events in
RT Arabidopsis thaliana using novel sequenced full-length cDNAs.";
RL DNA Res. 16:155-164(2009).
RN [5]
RP FUNCTION.
RX PubMed=22302148; DOI=10.1093/nar/gks034;
RA Xie M., Ren G., Costa-Nunes P., Pontes O., Yu B.;
RT "A subgroup of SGS3-like proteins act redundantly in RNA-directed DNA
RT methylation.";
RL Nucleic Acids Res. 40:4422-4431(2012).
CC -!- FUNCTION: Acts in association with FDM3 and FDM4 for RNA-directed DNA
CC methylation (RdDM). {ECO:0000269|PubMed:22302148}.
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DR EMBL; AC011713; AAF14667.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE36451.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM58618.1; -; Genomic_DNA.
DR EMBL; AK227040; BAE99100.1; -; mRNA.
DR EMBL; AK317564; BAH20228.1; -; mRNA.
DR PIR; E96840; E96840.
DR RefSeq; NP_001321040.1; NM_001335009.1.
DR RefSeq; NP_178194.1; NM_106727.4.
DR AlphaFoldDB; Q9SAI1; -.
DR SMR; Q9SAI1; -.
DR STRING; 3702.AT1G80790.1; -.
DR iPTMnet; Q9SAI1; -.
DR PaxDb; Q9SAI1; -.
DR PRIDE; Q9SAI1; -.
DR ProteomicsDB; 230619; -.
DR EnsemblPlants; AT1G80790.1; AT1G80790.1; AT1G80790.
DR EnsemblPlants; AT1G80790.2; AT1G80790.2; AT1G80790.
DR GeneID; 844418; -.
DR Gramene; AT1G80790.1; AT1G80790.1; AT1G80790.
DR Gramene; AT1G80790.2; AT1G80790.2; AT1G80790.
DR KEGG; ath:AT1G80790; -.
DR Araport; AT1G80790; -.
DR TAIR; locus:2825160; AT1G80790.
DR eggNOG; ENOG502QRE8; Eukaryota.
DR HOGENOM; CLU_021775_1_1_1; -.
DR InParanoid; Q9SAI1; -.
DR OMA; HKYNEQI; -.
DR OrthoDB; 635221at2759; -.
DR PhylomeDB; Q9SAI1; -.
DR PRO; PR:Q9SAI1; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SAI1; baseline and differential.
DR Genevisible; Q9SAI1; AT.
DR GO; GO:0080188; P:gene silencing by RNA-directed DNA methylation; IGI:TAIR.
DR CDD; cd12266; RRM_like_XS; 1.
DR Gene3D; 3.30.70.2890; -; 1.
DR InterPro; IPR045177; FDM1-5/IDN2.
DR InterPro; IPR005379; FDM1-5/IDN2_XH.
DR InterPro; IPR005380; XS_domain.
DR InterPro; IPR038588; XS_domain_sf.
DR InterPro; IPR005381; Znf-XS_domain.
DR PANTHER; PTHR21596; PTHR21596; 1.
DR Pfam; PF03469; XH; 1.
DR Pfam; PF03468; XS; 1.
DR Pfam; PF03470; zf-XS; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Reference proteome; RNA-mediated gene silencing.
FT CHAIN 1..634
FT /note="Factor of DNA methylation 5"
FT /id="PRO_0000430685"
FT COILED 254..469
FT /evidence="ECO:0000255"
FT CONFLICT 265
FT /note="M -> T (in Ref. 4; BAH20228)"
SQ SEQUENCE 634 AA; 74294 MW; 6EBA40FEA1A68451 CRC64;
MDNSSDEESE ISESEIDVYY EKPYEKLMNG DYKVKVKDTF RCPFCAGKKK QHYKYKELLA
HASGVAKGSA SRSAKQKANH FALAKYMENE LAGDADVPRP QIPSSSTEQS QAVVDDIYVW
PWMGIVINPV RRTDNKNVLL DSAYWLKKLA RFNPLEVKTL WLDQESVVAV IPQFNSGWSG
FKSVTELEKE YEIRGCGRKD WIDKRGDWRS KAYGWCARAD DYNSQGSIAE YLSKVGKLRS
FSDITKEEIQ NKSIVVDDLA NKIAMTNEDL NKLQYMNNEK TLSLRRVLIE KDELDRVYKQ
ETKKMQELSR EKINRIFREK ERLTNELEAK MNNLKIWSKQ LDKKQALTEL ERQKLDEDKK
KSDVMNSSLQ LASLEQKKTD DRVLRLVDEH KRKKEETLNK ILQLEKELDS KQKLQMEIQE
LKGKLKVMKH EDEDDEGIKK KMKKMKEELE EKCSELQDLE DTNSALMVKE RKSNDEIVEA
RKFLITELRE LVSDRNIIRV KRMGELEEKP FMTACRQRCT VEEEAQVQYA MLCSKWQEKV
KDSAWQPFKH VGTGDRKKEV VDEEDEEIKK LREEWGEEVK NAVKTALEEL NEFNPSGRYS
VPELWNSKQG RKATLKEVID YITQQVKTLK RRRA
