ID   3MGH_LEGPH              Reviewed;         183 AA.
AC   Q5ZX66;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Putative 3-methyladenine DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_00527};
DE            EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_00527};
GN   OrderedLocusNames=lpg0866;
OS   Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC
OS   33152 / DSM 7513).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Legionella.
OX   NCBI_TaxID=272624;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Philadelphia 1 / ATCC 33152 / DSM 7513;
RX   PubMed=15448271; DOI=10.1126/science.1099776;
RA   Chien M., Morozova I., Shi S., Sheng H., Chen J., Gomez S.M., Asamani G.,
RA   Hill K., Nuara J., Feder M., Rineer J., Greenberg J.J., Steshenko V.,
RA   Park S.H., Zhao B., Teplitskaya E., Edwards J.R., Pampou S., Georghiou A.,
RA   Chou I.-C., Iannuccilli W., Ulz M.E., Kim D.H., Geringer-Sameth A.,
RA   Goldsberry C., Morozov P., Fischer S.G., Segal G., Qu X., Rzhetsky A.,
RA   Zhang P., Cayanis E., De Jong P.J., Ju J., Kalachikov S., Shuman H.A.,
RA   Russo J.J.;
RT   "The genomic sequence of the accidental pathogen Legionella pneumophila.";
RL   Science 305:1966-1968(2004).
CC   -!- SIMILARITY: Belongs to the DNA glycosylase MPG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00527}.
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DR   EMBL; AE017354; AAU26954.1; -; Genomic_DNA.
DR   RefSeq; WP_010946602.1; NC_002942.5.
DR   RefSeq; YP_094901.1; NC_002942.5.
DR   AlphaFoldDB; Q5ZX66; -.
DR   SMR; Q5ZX66; -.
DR   STRING; 272624.lpg0866; -.
DR   PaxDb; Q5ZX66; -.
DR   EnsemblBacteria; AAU26954; AAU26954; lpg0866.
DR   GeneID; 66490048; -.
DR   KEGG; lpn:lpg0866; -.
DR   PATRIC; fig|272624.6.peg.898; -.
DR   eggNOG; COG2094; Bacteria.
DR   HOGENOM; CLU_060471_4_1_6; -.
DR   OMA; VEAYHHT; -.
DR   Proteomes; UP000000609; Chromosome.
DR   GO; GO:0003905; F:alkylbase DNA N-glycosylase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd00540; AAG; 1.
DR   Gene3D; 3.10.300.10; -; 1.
DR   HAMAP; MF_00527; 3MGH; 1.
DR   InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR   InterPro; IPR003180; MPG.
DR   InterPro; IPR036995; MPG_sf.
DR   PANTHER; PTHR10429; PTHR10429; 1.
DR   Pfam; PF02245; Pur_DNA_glyco; 1.
DR   SUPFAM; SSF50486; SSF50486; 1.
DR   TIGRFAMs; TIGR00567; 3mg; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Hydrolase; Reference proteome.
FT   CHAIN           1..183
FT                   /note="Putative 3-methyladenine DNA glycosylase"
FT                   /id="PRO_0000265032"
SQ   SEQUENCE   183 AA;  21028 MW;  8AEF075016AA2EE0 CRC64;
     MRKLLRPFYE RDTVLVAKEL LGKYLVHHDG LEEKIGRIVE VEAYLGQHDL ACHSSKGLTK
     RTKVMFGPAG YAYVYLIYGM YYCMNVVTEK EGIGSAVLIR ALEPIKNIQD RTQGPGLLSK
     AMRIDSKLNH RDLLSNDFYI AEPNSPTDFT IIEKPRIGVH YAKEWANELL RFYIKDNPYI
     SKT