ID   FASD_ECOLX              Reviewed;         835 AA.
AC   P46000;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Outer membrane usher protein FasD;
DE   Flags: Precursor;
GN   Name=fasD;
OS   Escherichia coli.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=987 / ETEC;
RX   PubMed=7906265; DOI=10.1128/jb.176.4.1099-1110.1994;
RA   Schifferli D.M., Alrutz M.A.;
RT   "Permissive linker insertion sites in the outer membrane protein of 987P
RT   fimbriae of Escherichia coli.";
RL   J. Bacteriol. 176:1099-1110(1994).
CC   -!- FUNCTION: Involved in the export and assembly of the 987P fimbriae
CC       subunits across the outer membrane.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the fimbrial export usher family. {ECO:0000305}.
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DR   EMBL; L22659; AAA21827.1; -; Genomic_DNA.
DR   EMBL; U50547; AAB02687.1; -; Genomic_DNA.
DR   PIR; A49891; A49891.
DR   RefSeq; WP_063079412.1; NZ_UCZI01000041.1.
DR   AlphaFoldDB; P46000; -.
DR   SMR; P46000; -.
DR   TCDB; 1.B.11.3.10; the outer membrane fimbrial usher porin (fup) family.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015473; F:fimbrial usher porin activity; IEA:InterPro.
DR   GO; GO:0009297; P:pilus assembly; IEA:InterPro.
DR   Gene3D; 2.60.40.2070; -; 1.
DR   Gene3D; 2.60.40.2610; -; 1.
DR   Gene3D; 3.10.20.410; -; 1.
DR   InterPro; IPR000015; Fimb_usher.
DR   InterPro; IPR018030; Fimbrial_membr_usher_CS.
DR   InterPro; IPR042186; FimD_plug_dom.
DR   InterPro; IPR025949; PapC-like_C.
DR   InterPro; IPR043142; PapC-like_C_sf.
DR   InterPro; IPR025885; PapC_N.
DR   InterPro; IPR037224; PapC_N_sf.
DR   PANTHER; PTHR30451; PTHR30451; 1.
DR   Pfam; PF13953; PapC_C; 1.
DR   Pfam; PF13954; PapC_N; 1.
DR   Pfam; PF00577; Usher; 1.
DR   SUPFAM; SSF141729; SSF141729; 1.
DR   PROSITE; PS01151; FIMBRIAL_USHER; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Disulfide bond; Fimbrium biogenesis; Membrane; Signal;
KW   Transmembrane; Transmembrane beta strand; Transport.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..835
FT                   /note="Outer membrane usher protein FasD"
FT                   /id="PRO_0000009310"
FT   DISULFID        810..834
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   835 AA;  92354 MW;  2FECE6E2305274E1 CRC64;
     MNKYPPLLTM LIIGIGSNAV AGDYFDPSLL ATDIGNNDKL DLSLFSHPGG GVKGEREVSV
     YINDFFYKNV TLDFENGISG ALEPIFPSGF FDNILASPYR SIKEKELIST ADFLSLVPYG
     MVRFDQAIAR VDISIPQAYL GRDAQMKSAP ESWNQGVPAL LIDYRLSGSK NKYNYGSSQN
     FYANAFLGFN LMGWRLRTTT NYMSYNSKDL YNKGERQGSF NFYNTYLEKD IGYLRSTLRL
     GELSTRGMIL ESFNFKGGKI YSNDEMLNDR LRSYTPTVRG IASSQAVVTI KQGGVVILQK
     NVPPGPFEIN DFSLSGYSGD LYVNIKEADG SEHSFIQPFS TLPEMKREGV SGYEISLGHY
     NNSGATQYYN ESPFLYASWS RGYRNGMTLY SETIQSRKYQ LLGVGSTLSL GDFGAVSGDA
     SLSRANKYDK IHSGQSYGLK YSKNKVDTGT TVTLATYRYS TKDFYSFNDF VSKNDSVQYV
     WDNRLKNRIT LSLNQSLDDY GSLSLIASQQ NYWTSDYVSR SFSLSHSFGW NDIFFSTSFS
     LDQKEGDNAL RNNNKVFGFY SSIPLSKLIG KNESTYSTLS YNVTKINNQV RNTATLAGKV
     PGSMAQYRFS SGWANTEQSS NKALSVNWDG DLLDGSLGYT SSGKNRITDY SLSGSAILYP
     WRLAIGSDSV INGAAVVETE FISGIKVRQG GETSLLGTAI VTSMQPYTEN RIDLDTQNIP
     DDLFISNASK KIVPEKGAVV PVKYNLFKGK QIVFSLKRYD GTPLPFGSVV SLVGSDSEIT
     GIIDDAGRVY LAGIPSKGIL HGAWGYNKSC EVSFNLNGKP SNNSNEIIEY EGVCK