ID   3MGH_FRATT              Reviewed;         193 AA.
AC   Q5NH09;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Putative 3-methyladenine DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_00527};
DE            EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_00527};
GN   OrderedLocusNames=FTT_0666c;
OS   Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Thiotrichales;
OC   Francisellaceae; Francisella.
OX   NCBI_TaxID=177416;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SCHU S4 / Schu 4;
RX   PubMed=15640799; DOI=10.1038/ng1499;
RA   Larsson P., Oyston P.C.F., Chain P., Chu M.C., Duffield M., Fuxelius H.-H.,
RA   Garcia E., Haelltorp G., Johansson D., Isherwood K.E., Karp P.D.,
RA   Larsson E., Liu Y., Michell S., Prior J., Prior R., Malfatti S.,
RA   Sjoestedt A., Svensson K., Thompson N., Vergez L., Wagg J.K., Wren B.W.,
RA   Lindler L.E., Andersson S.G.E., Forsman M., Titball R.W.;
RT   "The complete genome sequence of Francisella tularensis, the causative
RT   agent of tularemia.";
RL   Nat. Genet. 37:153-159(2005).
CC   -!- SIMILARITY: Belongs to the DNA glycosylase MPG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00527}.
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DR   EMBL; AJ749949; CAG45299.1; -; Genomic_DNA.
DR   RefSeq; WP_003020434.1; NZ_CP010290.1.
DR   RefSeq; YP_169683.1; NC_006570.2.
DR   AlphaFoldDB; Q5NH09; -.
DR   SMR; Q5NH09; -.
DR   STRING; 177416.FTT_0666c; -.
DR   DNASU; 3191052; -.
DR   EnsemblBacteria; CAG45299; CAG45299; FTT_0666c.
DR   KEGG; ftu:FTT_0666c; -.
DR   eggNOG; COG2094; Bacteria.
DR   OMA; VEAYHHT; -.
DR   Proteomes; UP000001174; Chromosome.
DR   GO; GO:0003905; F:alkylbase DNA N-glycosylase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd00540; AAG; 1.
DR   Gene3D; 3.10.300.10; -; 1.
DR   HAMAP; MF_00527; 3MGH; 1.
DR   InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR   InterPro; IPR003180; MPG.
DR   InterPro; IPR036995; MPG_sf.
DR   PANTHER; PTHR10429; PTHR10429; 1.
DR   Pfam; PF02245; Pur_DNA_glyco; 1.
DR   SUPFAM; SSF50486; SSF50486; 1.
DR   TIGRFAMs; TIGR00567; 3mg; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Hydrolase; Reference proteome.
FT   CHAIN           1..193
FT                   /note="Putative 3-methyladenine DNA glycosylase"
FT                   /id="PRO_0000265022"
SQ   SEQUENCE   193 AA;  21912 MW;  B669A04AADA610A3 CRC64;
     MNNLEAILRL KTIDAAKKLL GHFLVSKYNN KILIGKIVET EAYLYNDPAC HSYSNRTKRN
     SMMYAQAGTS YVYFTYGMHY CFNVVTADVG IGEAILIRAL EPIAGIEQMQ LNRSKTKLMD
     LCSGPAKLTQ ALNINLKDNG INLLDKDSSI LLRYNNDLIN EIDIVQTQRI GISKAKDMPY
     RFYIKDNIFV SKK