ID   3MGH_CLOD6              Reviewed;         202 AA.
AC   Q18C13;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Putative 3-methyladenine DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_00527};
DE            EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_00527};
GN   OrderedLocusNames=CD630_14930;
OS   Clostridioides difficile (strain 630) (Peptoclostridium difficile).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Peptostreptococcaceae;
OC   Clostridioides.
OX   NCBI_TaxID=272563;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=630;
RX   PubMed=16804543; DOI=10.1038/ng1830;
RA   Sebaihia M., Wren B.W., Mullany P., Fairweather N.F., Minton N.,
RA   Stabler R., Thomson N.R., Roberts A.P., Cerdeno-Tarraga A.M., Wang H.,
RA   Holden M.T.G., Wright A., Churcher C., Quail M.A., Baker S., Bason N.,
RA   Brooks K., Chillingworth T., Cronin A., Davis P., Dowd L., Fraser A.,
RA   Feltwell T., Hance Z., Holroyd S., Jagels K., Moule S., Mungall K.,
RA   Price C., Rabbinowitsch E., Sharp S., Simmonds M., Stevens K., Unwin L.,
RA   Whithead S., Dupuy B., Dougan G., Barrell B., Parkhill J.;
RT   "The multidrug-resistant human pathogen Clostridium difficile has a highly
RT   mobile, mosaic genome.";
RL   Nat. Genet. 38:779-786(2006).
CC   -!- SIMILARITY: Belongs to the DNA glycosylase MPG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00527}.
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DR   EMBL; AM180355; CAJ68358.1; -; Genomic_DNA.
DR   RefSeq; WP_003427435.1; NZ_CP010905.2.
DR   RefSeq; YP_001087994.1; NC_009089.1.
DR   AlphaFoldDB; Q18C13; -.
DR   SMR; Q18C13; -.
DR   STRING; 272563.CD630_14930; -.
DR   EnsemblBacteria; CAJ68358; CAJ68358; CD630_14930.
DR   GeneID; 66353899; -.
DR   KEGG; cdf:CD630_14930; -.
DR   KEGG; pdc:CDIF630_01658; -.
DR   PATRIC; fig|272563.120.peg.1562; -.
DR   eggNOG; COG2094; Bacteria.
DR   OMA; VEAYHHT; -.
DR   PhylomeDB; Q18C13; -.
DR   BioCyc; PDIF272563:G12WB-1630-MON; -.
DR   Proteomes; UP000001978; Chromosome.
DR   GO; GO:0003905; F:alkylbase DNA N-glycosylase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd00540; AAG; 1.
DR   Gene3D; 3.10.300.10; -; 1.
DR   HAMAP; MF_00527; 3MGH; 1.
DR   InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR   InterPro; IPR003180; MPG.
DR   InterPro; IPR036995; MPG_sf.
DR   PANTHER; PTHR10429; PTHR10429; 1.
DR   Pfam; PF02245; Pur_DNA_glyco; 1.
DR   SUPFAM; SSF50486; SSF50486; 1.
DR   TIGRFAMs; TIGR00567; 3mg; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Hydrolase; Reference proteome.
FT   CHAIN           1..202
FT                   /note="Putative 3-methyladenine DNA glycosylase"
FT                   /id="PRO_0000265009"
SQ   SEQUENCE   202 AA;  23472 MW;  ED208014FFF83DC3 CRC64;
     MEKDFFRKNG IDLAKSILGK YLIRKYENKV IVTKIIETEA YMGVNDKGAH VYGNKKTDRT
     KPLYLDGGHI YVYLIYGMYN CLNLSANIEN VPECVLIRGV EPITSLDEIS MNRYNKAYTE
     LSKYQVKNIT NGPGKLCKAL KIDRSLNSKS IMGEELYISD FYYDDKGKKV FSKDELDIKT
     SKRINIDYAE EAKDFLWRFY IE