ID   3MGH_CARHZ              Reviewed;         191 AA.
AC   Q3ABT8;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Putative 3-methyladenine DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_00527};
DE            EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_00527};
GN   OrderedLocusNames=CHY_1567;
OS   Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 /
OS   Z-2901).
OC   Bacteria; Firmicutes; Clostridia; Thermoanaerobacterales;
OC   Thermoanaerobacteraceae; Carboxydothermus.
OX   NCBI_TaxID=246194;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-161 / DSM 6008 / Z-2901;
RX   PubMed=16311624; DOI=10.1371/journal.pgen.0010065;
RA   Wu M., Ren Q., Durkin A.S., Daugherty S.C., Brinkac L.M., Dodson R.J.,
RA   Madupu R., Sullivan S.A., Kolonay J.F., Nelson W.C., Tallon L.J.,
RA   Jones K.M., Ulrich L.E., Gonzalez J.M., Zhulin I.B., Robb F.T., Eisen J.A.;
RT   "Life in hot carbon monoxide: the complete genome sequence of
RT   Carboxydothermus hydrogenoformans Z-2901.";
RL   PLoS Genet. 1:563-574(2005).
CC   -!- SIMILARITY: Belongs to the DNA glycosylase MPG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00527}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000141; ABB15839.1; -; Genomic_DNA.
DR   RefSeq; WP_011344471.1; NC_007503.1.
DR   AlphaFoldDB; Q3ABT8; -.
DR   SMR; Q3ABT8; -.
DR   STRING; 246194.CHY_1567; -.
DR   PRIDE; Q3ABT8; -.
DR   EnsemblBacteria; ABB15839; ABB15839; CHY_1567.
DR   KEGG; chy:CHY_1567; -.
DR   eggNOG; COG2094; Bacteria.
DR   HOGENOM; CLU_060471_4_1_9; -.
DR   OMA; VEAYHHT; -.
DR   OrthoDB; 1385409at2; -.
DR   Proteomes; UP000002706; Chromosome.
DR   GO; GO:0003905; F:alkylbase DNA N-glycosylase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd00540; AAG; 1.
DR   Gene3D; 3.10.300.10; -; 1.
DR   HAMAP; MF_00527; 3MGH; 1.
DR   InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR   InterPro; IPR003180; MPG.
DR   InterPro; IPR036995; MPG_sf.
DR   PANTHER; PTHR10429; PTHR10429; 1.
DR   Pfam; PF02245; Pur_DNA_glyco; 1.
DR   SUPFAM; SSF50486; SSF50486; 1.
DR   TIGRFAMs; TIGR00567; 3mg; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Hydrolase; Reference proteome.
FT   CHAIN           1..191
FT                   /note="Putative 3-methyladenine DNA glycosylase"
FT                   /id="PRO_0000265005"
SQ   SEQUENCE   191 AA;  21399 MW;  0F5B9DC72F834B57 CRC64;
     MLLPRQFYAR DVLIVAKDLL NCYLVREYNG HLLIGKIVET EAYHQNDPAC HAYRGKTKRN
     EVMFGPPGHA YVYFTYGMHY CFNVVTGAIG RAEAVLIRAL EPVKGIDIIK TLRGGKSERE
     LLSGPAKLTQ GLAIDLKLNG HDLTGGKILY ITKGEPVAEE DIVVTTRIGI NAGKDLPYRF
     YLKNNKYVSK K