ENKD1_HUMAN
ID ENKD1_HUMAN Reviewed; 346 AA.
AC Q9H0I2; Q6UWD7;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 151.
DE RecName: Full=Enkurin domain-containing protein 1;
GN Name=ENKD1; Synonyms=C16orf48; ORFNames=UNQ6410/PRO21183;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RX PubMed=11230166; DOI=10.1101/gr.gr1547r;
RA Wiemann S., Weil B., Wellenreuther R., Gassenhuber J., Glassl S.,
RA Ansorge W., Boecher M., Bloecker H., Bauersachs S., Blum H., Lauber J.,
RA Duesterhoeft A., Beyer A., Koehrer K., Strack N., Mewes H.-W.,
RA Ottenwaelder B., Obermaier B., Tampe J., Heubner D., Wambutt R., Korn B.,
RA Klein M., Poustka A.;
RT "Towards a catalog of human genes and proteins: sequencing and analysis of
RT 500 novel complete protein coding human cDNAs.";
RL Genome Res. 11:422-435(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RX PubMed=12975309; DOI=10.1101/gr.1293003;
RA Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J.,
RA Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P.,
RA Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E., Heldens S., Huang A.,
RA Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D.,
RA Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L.,
RA Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C.,
RA Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J.,
RA Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M.;
RT "The secreted protein discovery initiative (SPDI), a large-scale effort to
RT identify novel human secreted and transmembrane proteins: a bioinformatics
RT assessment.";
RL Genome Res. 13:2265-2270(2003).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Placenta;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-91 AND SER-136, AND
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Cervix carcinoma, and Erythroleukemia;
RX PubMed=23186163; DOI=10.1021/pr300630k;
RA Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J.,
RA Mohammed S.;
RT "Toward a comprehensive characterization of a human cancer cell
RT phosphoproteome.";
RL J. Proteome Res. 12:260-271(2013).
CC -!- INTERACTION:
CC Q9H0I2; Q8IZP0-5: ABI1; NbExp=3; IntAct=EBI-744099, EBI-11743294;
CC Q9H0I2; Q9NYB9-2: ABI2; NbExp=6; IntAct=EBI-744099, EBI-11096309;
CC Q9H0I2; O00154-4: ACOT7; NbExp=3; IntAct=EBI-744099, EBI-12007918;
CC Q9H0I2; Q9ULX6: AKAP8L; NbExp=3; IntAct=EBI-744099, EBI-357530;
CC Q9H0I2; Q86SG2: ANKRD23; NbExp=3; IntAct=EBI-744099, EBI-5661893;
CC Q9H0I2; Q8WVL7: ANKRD49; NbExp=3; IntAct=EBI-744099, EBI-9381820;
CC Q9H0I2; Q96C12: ARMC5; NbExp=3; IntAct=EBI-744099, EBI-6425121;
CC Q9H0I2; P15289: ARSA; NbExp=3; IntAct=EBI-744099, EBI-2117357;
CC Q9H0I2; Q9Y575-3: ASB3; NbExp=3; IntAct=EBI-744099, EBI-14199987;
CC Q9H0I2; Q5T686: AVPI1; NbExp=3; IntAct=EBI-744099, EBI-8640233;
CC Q9H0I2; Q8N9N5-2: BANP; NbExp=3; IntAct=EBI-744099, EBI-11524452;
CC Q9H0I2; O75934: BCAS2; NbExp=3; IntAct=EBI-744099, EBI-1050106;
CC Q9H0I2; Q8TDM0-3: BCAS4; NbExp=3; IntAct=EBI-744099, EBI-13025473;
CC Q9H0I2; Q9BUH8: BEGAIN; NbExp=4; IntAct=EBI-744099, EBI-742722;
CC Q9H0I2; Q00994: BEX3; NbExp=3; IntAct=EBI-744099, EBI-741753;
CC Q9H0I2; Q6PI77: BHLHB9; NbExp=3; IntAct=EBI-744099, EBI-11519926;
CC Q9H0I2; Q9H2G9: BLZF1; NbExp=5; IntAct=EBI-744099, EBI-2548012;
CC Q9H0I2; Q6PJG6: BRAT1; NbExp=3; IntAct=EBI-744099, EBI-10826195;
CC Q9H0I2; Q5BKX5-3: C19orf54; NbExp=3; IntAct=EBI-744099, EBI-11976299;
CC Q9H0I2; O95561: C1orf105; NbExp=3; IntAct=EBI-744099, EBI-10191951;
CC Q9H0I2; Q9P1Z2: CALCOCO1; NbExp=3; IntAct=EBI-744099, EBI-749920;
CC Q9H0I2; Q13137: CALCOCO2; NbExp=4; IntAct=EBI-744099, EBI-739580;
CC Q9H0I2; Q9Y3M2: CBY1; NbExp=3; IntAct=EBI-744099, EBI-947308;
CC Q9H0I2; Q8NA61: CBY2; NbExp=3; IntAct=EBI-744099, EBI-741724;
CC Q9H0I2; Q8NA61-2: CBY2; NbExp=3; IntAct=EBI-744099, EBI-11524851;
CC Q9H0I2; Q68D86: CCDC102B; NbExp=6; IntAct=EBI-744099, EBI-10171570;
CC Q9H0I2; Q8IYE1: CCDC13; NbExp=3; IntAct=EBI-744099, EBI-10961312;
CC Q9H0I2; Q96JN2-2: CCDC136; NbExp=3; IntAct=EBI-744099, EBI-10171416;
CC Q9H0I2; Q9BUN5-3: CCDC28B; NbExp=3; IntAct=EBI-744099, EBI-12920646;
CC Q9H0I2; Q9BXL8: CDCA4; NbExp=3; IntAct=EBI-744099, EBI-1773949;
CC Q9H0I2; Q6NVV7: CDPF1; NbExp=3; IntAct=EBI-744099, EBI-2802782;
CC Q9H0I2; Q01850: CDR2; NbExp=6; IntAct=EBI-744099, EBI-1181367;
CC Q9H0I2; Q53EZ4: CEP55; NbExp=3; IntAct=EBI-744099, EBI-747776;
CC Q9H0I2; Q8NHQ1: CEP70; NbExp=4; IntAct=EBI-744099, EBI-739624;
CC Q9H0I2; Q9NX63: CHCHD3; NbExp=3; IntAct=EBI-744099, EBI-743375;
CC Q9H0I2; Q9UKJ5: CHIC2; NbExp=3; IntAct=EBI-744099, EBI-741528;
CC Q9H0I2; Q6WN34-2: CHRDL2; NbExp=3; IntAct=EBI-744099, EBI-12593838;
CC Q9H0I2; Q96BR5: COA7; NbExp=3; IntAct=EBI-744099, EBI-6269632;
CC Q9H0I2; P56545-3: CTBP2; NbExp=3; IntAct=EBI-744099, EBI-10171902;
CC Q9H0I2; A8MQ03: CYSRT1; NbExp=3; IntAct=EBI-744099, EBI-3867333;
CC Q9H0I2; Q8WWB3: DYDC1; NbExp=3; IntAct=EBI-744099, EBI-740680;
CC Q9H0I2; Q16610: ECM1; NbExp=3; IntAct=EBI-744099, EBI-947964;
CC Q9H0I2; Q5JST6: EFHC2; NbExp=3; IntAct=EBI-744099, EBI-2349927;
CC Q9H0I2; Q04637-9: EIF4G1; NbExp=3; IntAct=EBI-744099, EBI-12012124;
CC Q9H0I2; O00167-2: EYA2; NbExp=3; IntAct=EBI-744099, EBI-12807776;
CC Q9H0I2; Q86X51: EZHIP; NbExp=3; IntAct=EBI-744099, EBI-12827735;
CC Q9H0I2; Q5T9C2: FAM102A; NbExp=3; IntAct=EBI-744099, EBI-10246318;
CC Q9H0I2; Q86W67: FAM228A; NbExp=3; IntAct=EBI-744099, EBI-12958227;
CC Q9H0I2; Q86YD7: FAM90A1; NbExp=3; IntAct=EBI-744099, EBI-6658203;
CC Q9H0I2; O94868-3: FCHSD2; NbExp=3; IntAct=EBI-744099, EBI-11958845;
CC Q9H0I2; O75344: FKBP6; NbExp=3; IntAct=EBI-744099, EBI-744771;
CC Q9H0I2; P01100: FOS; NbExp=3; IntAct=EBI-744099, EBI-852851;
CC Q9H0I2; P53539: FOSB; NbExp=3; IntAct=EBI-744099, EBI-2806743;
CC Q9H0I2; O95073: FSBP; NbExp=3; IntAct=EBI-744099, EBI-1059030;
CC Q9H0I2; A1L4K1: FSD2; NbExp=3; IntAct=EBI-744099, EBI-5661036;
CC Q9H0I2; O95257: GADD45G; NbExp=5; IntAct=EBI-744099, EBI-448202;
CC Q9H0I2; Q8TAE8: GADD45GIP1; NbExp=3; IntAct=EBI-744099, EBI-372506;
CC Q9H0I2; Q7L5D6: GET4; NbExp=3; IntAct=EBI-744099, EBI-711823;
CC Q9H0I2; P14136: GFAP; NbExp=3; IntAct=EBI-744099, EBI-744302;
CC Q9H0I2; O75420: GIGYF1; NbExp=3; IntAct=EBI-744099, EBI-947774;
CC Q9H0I2; Q08379: GOLGA2; NbExp=3; IntAct=EBI-744099, EBI-618309;
CC Q9H0I2; Q9NYA3: GOLGA6A; NbExp=3; IntAct=EBI-744099, EBI-11163335;
CC Q9H0I2; A6NEM1: GOLGA6L9; NbExp=3; IntAct=EBI-744099, EBI-5916454;
CC Q9H0I2; Q8TE85-2: GRHL3; NbExp=3; IntAct=EBI-744099, EBI-12827521;
CC Q9H0I2; Q4V328: GRIPAP1; NbExp=3; IntAct=EBI-744099, EBI-717919;
CC Q9H0I2; Q6NT76: HMBOX1; NbExp=3; IntAct=EBI-744099, EBI-2549423;
CC Q9H0I2; Q9UGU5: HMGXB4; NbExp=3; IntAct=EBI-744099, EBI-7261162;
CC Q9H0I2; P31943: HNRNPH1; NbExp=3; IntAct=EBI-744099, EBI-351590;
CC Q9H0I2; Q96ED9-2: HOOK2; NbExp=3; IntAct=EBI-744099, EBI-10961706;
CC Q9H0I2; P49639: HOXA1; NbExp=5; IntAct=EBI-744099, EBI-740785;
CC Q9H0I2; O75031: HSF2BP; NbExp=3; IntAct=EBI-744099, EBI-7116203;
CC Q9H0I2; Q16082: HSPB2; NbExp=3; IntAct=EBI-744099, EBI-739395;
CC Q9H0I2; Q02363: ID2; NbExp=3; IntAct=EBI-744099, EBI-713450;
CC Q9H0I2; P05019-2: IGF1; NbExp=3; IntAct=EBI-744099, EBI-12837046;
CC Q9H0I2; P24592: IGFBP6; NbExp=3; IntAct=EBI-744099, EBI-947015;
CC Q9H0I2; Q9Y6K9: IKBKG; NbExp=3; IntAct=EBI-744099, EBI-81279;
CC Q9H0I2; Q9UKT9: IKZF3; NbExp=3; IntAct=EBI-744099, EBI-747204;
CC Q9H0I2; Q96N16: JAKMIP1; NbExp=3; IntAct=EBI-744099, EBI-2680803;
CC Q9H0I2; Q86T90: KIAA1328; NbExp=3; IntAct=EBI-744099, EBI-3437878;
CC Q9H0I2; Q9BVG8-5: KIFC3; NbExp=3; IntAct=EBI-744099, EBI-14069005;
CC Q9H0I2; Q9BS75: KLHL20; NbExp=3; IntAct=EBI-744099, EBI-10693436;
CC Q9H0I2; Q53HC5: KLHL26; NbExp=3; IntAct=EBI-744099, EBI-724915;
CC Q9H0I2; P02533: KRT14; NbExp=3; IntAct=EBI-744099, EBI-702178;
CC Q9H0I2; P19012: KRT15; NbExp=3; IntAct=EBI-744099, EBI-739566;
CC Q9H0I2; Q15323: KRT31; NbExp=3; IntAct=EBI-744099, EBI-948001;
CC Q9H0I2; Q92764: KRT35; NbExp=3; IntAct=EBI-744099, EBI-1058674;
CC Q9H0I2; Q6A162: KRT40; NbExp=3; IntAct=EBI-744099, EBI-10171697;
CC Q9H0I2; P60370: KRTAP10-5; NbExp=3; IntAct=EBI-744099, EBI-10172150;
CC Q9H0I2; P60410: KRTAP10-8; NbExp=3; IntAct=EBI-744099, EBI-10171774;
CC Q9H0I2; Q8IUC1: KRTAP11-1; NbExp=3; IntAct=EBI-744099, EBI-1052037;
CC Q9H0I2; P59990: KRTAP12-1; NbExp=3; IntAct=EBI-744099, EBI-10210845;
CC Q9H0I2; Q52LG2: KRTAP13-2; NbExp=3; IntAct=EBI-744099, EBI-11953846;
CC Q9H0I2; Q8IUB9: KRTAP19-1; NbExp=3; IntAct=EBI-744099, EBI-12811111;
CC Q9H0I2; Q3LI72: KRTAP19-5; NbExp=3; IntAct=EBI-744099, EBI-1048945;
CC Q9H0I2; Q3LI70: KRTAP19-6; NbExp=3; IntAct=EBI-744099, EBI-12805508;
CC Q9H0I2; Q9BYQ6: KRTAP4-11; NbExp=3; IntAct=EBI-744099, EBI-10302392;
CC Q9H0I2; P26371: KRTAP5-9; NbExp=3; IntAct=EBI-744099, EBI-3958099;
CC Q9H0I2; Q3LI66: KRTAP6-2; NbExp=3; IntAct=EBI-744099, EBI-11962084;
CC Q9H0I2; Q8IYD9: LAS2; NbExp=3; IntAct=EBI-744099, EBI-749878;
CC Q9H0I2; O95751: LDOC1; NbExp=3; IntAct=EBI-744099, EBI-740738;
CC Q9H0I2; Q9UBR4-2: LHX3; NbExp=3; IntAct=EBI-744099, EBI-12039345;
CC Q9H0I2; Q9HAP6: LIN7B; NbExp=3; IntAct=EBI-744099, EBI-821335;
CC Q9H0I2; P25791-3: LMO2; NbExp=3; IntAct=EBI-744099, EBI-11959475;
CC Q9H0I2; Q9BV99: LRRC61; NbExp=3; IntAct=EBI-744099, EBI-2350424;
CC Q9H0I2; Q96LR2: LURAP1; NbExp=3; IntAct=EBI-744099, EBI-741355;
CC Q9H0I2; Q9Y250: LZTS1; NbExp=3; IntAct=EBI-744099, EBI-1216080;
CC Q9H0I2; P45984: MAPK9; NbExp=3; IntAct=EBI-744099, EBI-713568;
CC Q9H0I2; O95460-2: MATN4; NbExp=3; IntAct=EBI-744099, EBI-12072296;
CC Q9H0I2; Q99750: MDFI; NbExp=8; IntAct=EBI-744099, EBI-724076;
CC Q9H0I2; Q99687-3: MEIS3; NbExp=3; IntAct=EBI-744099, EBI-18582591;
CC Q9H0I2; Q14696: MESD; NbExp=3; IntAct=EBI-744099, EBI-6165891;
CC Q9H0I2; Q8N6F8: METTL27; NbExp=3; IntAct=EBI-744099, EBI-8487781;
CC Q9H0I2; Q9UJV3-2: MID2; NbExp=3; IntAct=EBI-744099, EBI-10172526;
CC Q9H0I2; A9UHW6-2: MIF4GD; NbExp=3; IntAct=EBI-744099, EBI-9118295;
CC Q9H0I2; Q8TD10: MIPOL1; NbExp=6; IntAct=EBI-744099, EBI-2548751;
CC Q9H0I2; Q8IVT2: MISP; NbExp=3; IntAct=EBI-744099, EBI-2555085;
CC Q9H0I2; Q13064: MKRN3; NbExp=4; IntAct=EBI-744099, EBI-2340269;
CC Q9H0I2; P40692: MLH1; NbExp=3; IntAct=EBI-744099, EBI-744248;
CC Q9H0I2; Q6PF18: MORN3; NbExp=3; IntAct=EBI-744099, EBI-9675802;
CC Q9H0I2; Q5VZ52: MORN5; NbExp=3; IntAct=EBI-744099, EBI-12835568;
CC Q9H0I2; Q6NTE8: MRNIP; NbExp=3; IntAct=EBI-744099, EBI-2857471;
CC Q9H0I2; Q13084: MRPL28; NbExp=3; IntAct=EBI-744099, EBI-723426;
CC Q9H0I2; Q96DV4: MRPL38; NbExp=3; IntAct=EBI-744099, EBI-720441;
CC Q9H0I2; Q5JR59-3: MTUS2; NbExp=3; IntAct=EBI-744099, EBI-11522433;
CC Q9H0I2; P13349: MYF5; NbExp=5; IntAct=EBI-744099, EBI-17491620;
CC Q9H0I2; Q8TDC0: MYOZ3; NbExp=3; IntAct=EBI-744099, EBI-5662487;
CC Q9H0I2; O15049: N4BP3; NbExp=3; IntAct=EBI-744099, EBI-2512055;
CC Q9H0I2; Q15742: NAB2; NbExp=3; IntAct=EBI-744099, EBI-8641936;
CC Q9H0I2; Q9NZQ3-3: NCKIPSD; NbExp=3; IntAct=EBI-744099, EBI-10963850;
CC Q9H0I2; P17568: NDUFB7; NbExp=3; IntAct=EBI-744099, EBI-1246238;
CC Q9H0I2; I6L9F6: NEFL; NbExp=3; IntAct=EBI-744099, EBI-10178578;
CC Q9H0I2; P25963: NFKBIA; NbExp=3; IntAct=EBI-744099, EBI-307386;
CC Q9H0I2; P0CG21: NHLRC4; NbExp=3; IntAct=EBI-744099, EBI-12868744;
CC Q9H0I2; A6NGQ2: OOEP; NbExp=3; IntAct=EBI-744099, EBI-18583589;
CC Q9H0I2; Q9P286: PAK5; NbExp=3; IntAct=EBI-744099, EBI-741896;
CC Q9H0I2; Q9NVD7: PARVA; NbExp=3; IntAct=EBI-744099, EBI-747655;
CC Q9H0I2; Q9NR12: PDLIM7; NbExp=6; IntAct=EBI-744099, EBI-350517;
CC Q9H0I2; Q17RL8: PDZD4; NbExp=3; IntAct=EBI-744099, EBI-10239064;
CC Q9H0I2; Q8IXK0: PHC2; NbExp=4; IntAct=EBI-744099, EBI-713786;
CC Q9H0I2; Q4G0R1: PIBF1; NbExp=3; IntAct=EBI-744099, EBI-14066006;
CC Q9H0I2; Q9NRD5: PICK1; NbExp=3; IntAct=EBI-744099, EBI-79165;
CC Q9H0I2; Q8WWB5: PIH1D2; NbExp=3; IntAct=EBI-744099, EBI-10232538;
CC Q9H0I2; Q92569: PIK3R3; NbExp=3; IntAct=EBI-744099, EBI-79893;
CC Q9H0I2; Q96KN3: PKNOX2; NbExp=3; IntAct=EBI-744099, EBI-2692890;
CC Q9H0I2; Q8ND90: PNMA1; NbExp=4; IntAct=EBI-744099, EBI-302345;
CC Q9H0I2; Q9UL42: PNMA2; NbExp=7; IntAct=EBI-744099, EBI-302355;
CC Q9H0I2; Q9BUI4: POLR3C; NbExp=3; IntAct=EBI-744099, EBI-5452779;
CC Q9H0I2; Q969Q6: PPP2R3C; NbExp=3; IntAct=EBI-744099, EBI-2561661;
CC Q9H0I2; Q9GZV8: PRDM14; NbExp=3; IntAct=EBI-744099, EBI-3957793;
CC Q9H0I2; Q9NQX0: PRDM6; NbExp=3; IntAct=EBI-744099, EBI-11320284;
CC Q9H0I2; Q9BYM8: RBCK1; NbExp=3; IntAct=EBI-744099, EBI-2340624;
CC Q9H0I2; P57052: RBM11; NbExp=3; IntAct=EBI-744099, EBI-741332;
CC Q9H0I2; Q15293: RCN1; NbExp=3; IntAct=EBI-744099, EBI-948278;
CC Q9H0I2; Q92622: RUBCN; NbExp=3; IntAct=EBI-744099, EBI-2952709;
CC Q9H0I2; Q59EK9-3: RUNDC3A; NbExp=3; IntAct=EBI-744099, EBI-11957366;
CC Q9H0I2; Q9UJW9: SERTAD3; NbExp=3; IntAct=EBI-744099, EBI-748621;
CC Q9H0I2; Q16348: SLC15A2; NbExp=3; IntAct=EBI-744099, EBI-12806032;
CC Q9H0I2; Q9H7B4: SMYD3; NbExp=3; IntAct=EBI-744099, EBI-347919;
CC Q9H0I2; Q6IEG0: SNRNP48; NbExp=3; IntAct=EBI-744099, EBI-2876632;
CC Q9H0I2; O60504: SORBS3; NbExp=3; IntAct=EBI-744099, EBI-741237;
CC Q9H0I2; Q5T0L3: SPATA46; NbExp=3; IntAct=EBI-744099, EBI-750105;
CC Q9H0I2; O95238: SPDEF; NbExp=3; IntAct=EBI-744099, EBI-12811275;
CC Q9H0I2; Q92563: SPOCK2; NbExp=3; IntAct=EBI-744099, EBI-311086;
CC Q9H0I2; Q6PJ21: SPSB3; NbExp=6; IntAct=EBI-744099, EBI-3937206;
CC Q9H0I2; Q8IXS7: SRGAP3; NbExp=3; IntAct=EBI-744099, EBI-18616594;
CC Q9H0I2; Q96MF2: STAC3; NbExp=4; IntAct=EBI-744099, EBI-745680;
CC Q9H0I2; Q9NZ72: STMN3; NbExp=3; IntAct=EBI-744099, EBI-725557;
CC Q9H0I2; Q08AL9: STXBP4; NbExp=3; IntAct=EBI-744099, EBI-10318905;
CC Q9H0I2; Q96A09: TENT5B; NbExp=3; IntAct=EBI-744099, EBI-752030;
CC Q9H0I2; P19237: TNNI1; NbExp=3; IntAct=EBI-744099, EBI-746692;
CC Q9H0I2; Q63HR2: TNS2; NbExp=3; IntAct=EBI-744099, EBI-949753;
CC Q9H0I2; Q96NM4-3: TOX2; NbExp=3; IntAct=EBI-744099, EBI-12815137;
CC Q9H0I2; Q13077: TRAF1; NbExp=3; IntAct=EBI-744099, EBI-359224;
CC Q9H0I2; Q12933: TRAF2; NbExp=7; IntAct=EBI-744099, EBI-355744;
CC Q9H0I2; P36406: TRIM23; NbExp=3; IntAct=EBI-744099, EBI-740098;
CC Q9H0I2; P14373: TRIM27; NbExp=3; IntAct=EBI-744099, EBI-719493;
CC Q9H0I2; Q9UPQ4-2: TRIM35; NbExp=3; IntAct=EBI-744099, EBI-17716262;
CC Q9H0I2; Q9BYV2: TRIM54; NbExp=6; IntAct=EBI-744099, EBI-2130429;
CC Q9H0I2; Q86WV8: TSC1; NbExp=3; IntAct=EBI-744099, EBI-12806590;
CC Q9H0I2; Q8WW01: TSEN15; NbExp=3; IntAct=EBI-744099, EBI-372432;
CC Q9H0I2; Q5W5X9-3: TTC23; NbExp=3; IntAct=EBI-744099, EBI-9090990;
CC Q9H0I2; Q5T124: UBXN11; NbExp=3; IntAct=EBI-744099, EBI-746004;
CC Q9H0I2; Q5T124-6: UBXN11; NbExp=3; IntAct=EBI-744099, EBI-11524408;
CC Q9H0I2; Q9Y6N9-4: USH1C; NbExp=3; IntAct=EBI-744099, EBI-11523636;
CC Q9H0I2; Q495M9: USH1G; NbExp=3; IntAct=EBI-744099, EBI-8601749;
CC Q9H0I2; Q8N6Y0: USHBP1; NbExp=3; IntAct=EBI-744099, EBI-739895;
CC Q9H0I2; A0A024R8A9: USP20; NbExp=3; IntAct=EBI-744099, EBI-14096082;
CC Q9H0I2; P61758: VBP1; NbExp=3; IntAct=EBI-744099, EBI-357430;
CC Q9H0I2; Q9H9H4: VPS37B; NbExp=3; IntAct=EBI-744099, EBI-4400866;
CC Q9H0I2; Q2TAL6: VWC2; NbExp=3; IntAct=EBI-744099, EBI-11957238;
CC Q9H0I2; O43379: WDR62; NbExp=4; IntAct=EBI-744099, EBI-714790;
CC Q9H0I2; Q9NZC7-5: WWOX; NbExp=3; IntAct=EBI-744099, EBI-12040603;
CC Q9H0I2; O43829: ZBTB14; NbExp=3; IntAct=EBI-744099, EBI-10176632;
CC Q9H0I2; Q53FD0-2: ZC2HC1C; NbExp=3; IntAct=EBI-744099, EBI-14104088;
CC Q9H0I2; Q8TF47: ZFP90; NbExp=3; IntAct=EBI-744099, EBI-11419867;
CC Q9H0I2; P52747: ZNF143; NbExp=3; IntAct=EBI-744099, EBI-2849334;
CC Q9H0I2; Q9BUY5: ZNF426; NbExp=3; IntAct=EBI-744099, EBI-743265;
CC Q9H0I2; Q9C0F3: ZNF436; NbExp=3; IntAct=EBI-744099, EBI-8489702;
CC Q9H0I2; Q8NB15: ZNF511; NbExp=3; IntAct=EBI-744099, EBI-10269136;
CC Q9H0I2; Q9P0T4: ZNF581; NbExp=3; IntAct=EBI-744099, EBI-745520;
CC Q9H0I2; P36508: ZNF76; NbExp=3; IntAct=EBI-744099, EBI-7254550;
CC Q9H0I2; Q6NX45: ZNF774; NbExp=3; IntAct=EBI-744099, EBI-10251462;
CC Q9H0I2; Q9UGI0: ZRANB1; NbExp=3; IntAct=EBI-744099, EBI-527853;
CC Q9H0I2; A0A1U9X8X8; NbExp=3; IntAct=EBI-744099, EBI-17234977;
CC Q9H0I2; Q6ZN96; NbExp=3; IntAct=EBI-744099, EBI-10255097;
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9H0I2-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9H0I2-2; Sequence=VSP_021904, VSP_021905;
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DR EMBL; AL136786; CAB66720.1; -; mRNA.
DR EMBL; AY358834; AAQ89193.1; -; mRNA.
DR EMBL; BC008284; AAH08284.1; -; mRNA.
DR CCDS; CCDS10844.1; -. [Q9H0I2-1]
DR RefSeq; NP_115516.1; NM_032140.2. [Q9H0I2-1]
DR AlphaFoldDB; Q9H0I2; -.
DR SMR; Q9H0I2; -.
DR BioGRID; 123875; 218.
DR IntAct; Q9H0I2; 223.
DR MINT; Q9H0I2; -.
DR STRING; 9606.ENSP00000243878; -.
DR iPTMnet; Q9H0I2; -.
DR PhosphoSitePlus; Q9H0I2; -.
DR BioMuta; ENKD1; -.
DR DMDM; 74752565; -.
DR EPD; Q9H0I2; -.
DR jPOST; Q9H0I2; -.
DR MassIVE; Q9H0I2; -.
DR MaxQB; Q9H0I2; -.
DR PaxDb; Q9H0I2; -.
DR PeptideAtlas; Q9H0I2; -.
DR PRIDE; Q9H0I2; -.
DR ProteomicsDB; 80281; -. [Q9H0I2-1]
DR ProteomicsDB; 80282; -. [Q9H0I2-2]
DR Antibodypedia; 29606; 127 antibodies from 17 providers.
DR DNASU; 84080; -.
DR Ensembl; ENST00000243878.9; ENSP00000243878.4; ENSG00000124074.12. [Q9H0I2-1]
DR GeneID; 84080; -.
DR KEGG; hsa:84080; -.
DR MANE-Select; ENST00000243878.9; ENSP00000243878.4; NM_032140.3; NP_115516.1.
DR UCSC; uc002etw.2; human. [Q9H0I2-1]
DR CTD; 84080; -.
DR DisGeNET; 84080; -.
DR GeneCards; ENKD1; -.
DR HGNC; HGNC:25246; ENKD1.
DR HPA; ENSG00000124074; Tissue enhanced (pancreas).
DR neXtProt; NX_Q9H0I2; -.
DR OpenTargets; ENSG00000124074; -.
DR PharmGKB; PA142672256; -.
DR VEuPathDB; HostDB:ENSG00000124074; -.
DR eggNOG; ENOG502QU1P; Eukaryota.
DR GeneTree; ENSGT00940000153866; -.
DR HOGENOM; CLU_068901_0_0_1; -.
DR InParanoid; Q9H0I2; -.
DR OMA; QRRCKEQ; -.
DR OrthoDB; 1383928at2759; -.
DR PhylomeDB; Q9H0I2; -.
DR TreeFam; TF328494; -.
DR PathwayCommons; Q9H0I2; -.
DR SignaLink; Q9H0I2; -.
DR BioGRID-ORCS; 84080; 23 hits in 1077 CRISPR screens.
DR ChiTaRS; ENKD1; human.
DR GeneWiki; C16orf48; -.
DR GenomeRNAi; 84080; -.
DR Pharos; Q9H0I2; Tdark.
DR PRO; PR:Q9H0I2; -.
DR Proteomes; UP000005640; Chromosome 16.
DR RNAct; Q9H0I2; protein.
DR Bgee; ENSG00000124074; Expressed in body of pancreas and 155 other tissues.
DR ExpressionAtlas; Q9H0I2; baseline and differential.
DR Genevisible; Q9H0I2; HS.
DR GO; GO:0097731; C:9+0 non-motile cilium; IEA:Ensembl.
DR GO; GO:0097546; C:ciliary base; IEA:Ensembl.
DR GO; GO:0005881; C:cytoplasmic microtubule; IDA:UniProtKB.
DR GO; GO:0015630; C:microtubule cytoskeleton; IDA:LIFEdb.
DR InterPro; IPR027710; ENKD1.
DR InterPro; IPR027012; Enkurin_dom.
DR PANTHER; PTHR21490:SF2; PTHR21490:SF2; 1.
DR Pfam; PF13864; Enkurin; 1.
DR PROSITE; PS51665; ENKURIN; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Phosphoprotein; Reference proteome.
FT CHAIN 1..346
FT /note="Enkurin domain-containing protein 1"
FT /id="PRO_0000265931"
FT DOMAIN 251..343
FT /note="Enkurin"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01000"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 114..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 167..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 260..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..192
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 91
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:23186163"
FT MOD_RES 136
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:23186163"
FT VAR_SEQ 1..118
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:12975309"
FT /id="VSP_021904"
FT VAR_SEQ 119..149
FT /note="ERSREQGQPRPLKALWRSPKYDKVESRVKAQ -> MDAKVRRAKMARVLQLE
FT PQTSACLLSLLCPA (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:12975309"
FT /id="VSP_021905"
SQ SEQUENCE 346 AA; 38759 MW; EDB07D64A0BB23FF CRC64;
MCEGPSRISG PIPPDPTLCP DNYRRPTSAQ GRLEGNALKL DLLTSDRALD TTAPRGPCIG
PGAGEILERG QRGVGDVLLQ LEGISLGPGA SLKRKDPKDH EKENLRRIRE IQKRFREQER
SREQGQPRPL KALWRSPKYD KVESRVKAQL QEPGPASGTE SAHFLRAHSR CGPGLPPPHV
SSPQPTPPGP EAKEPGLGVD FIRHNARAAK RAPRRHSCSL QVLAQVLEQQ RQAQEHYNAT
QKGHVPHYLL ERRDLWRREA EARKQSQPDP AMPPGHTRMP ENQRLETLTK LLQSQSQLLR
ELVLLPAGAD SLRAQSHRAE LDRKLVQVEE AIKIFSRPKV FVKMDD
