ID   EFG1P_CRYNJ             Reviewed;         286 AA.
AC   P0CN34; Q55HI6; Q5K724;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   25-MAY-2022, entry version 28.
DE   RecName: Full=rRNA-processing protein EFG1;
GN   Name=EFG1; OrderedLocusNames=CNN01370;
OS   Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS   MYA-565) (Filobasidiella neoformans).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Cryptococcus;
OC   Cryptococcus neoformans species complex.
OX   NCBI_TaxID=214684;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JEC21 / ATCC MYA-565;
RX   PubMed=15653466; DOI=10.1126/science.1103773;
RA   Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA   Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA   Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA   Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA   Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J.,
RA   Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA   Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA   Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA   Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA   Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT   "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT   neoformans.";
RL   Science 307:1321-1324(2005).
CC   -!- FUNCTION: Involved in rRNA processing. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EFG1 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAW47082.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AE017356; AAW47082.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_568599.1; XM_568599.1.
DR   AlphaFoldDB; P0CN34; -.
DR   SMR; P0CN34; -.
DR   STRING; 5207.AAW47082; -.
DR   EnsemblFungi; AAW47082; AAW47082; CNN01370.
DR   VEuPathDB; FungiDB:CNN01370; -.
DR   eggNOG; KOG4484; Eukaryota.
DR   InParanoid; P0CN34; -.
DR   OrthoDB; 1514264at2759; -.
DR   Proteomes; UP000002149; Chromosome 14.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0030688; C:preribosome, small subunit precursor; IBA:GO_Central.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   InterPro; IPR019310; Efg1.
DR   Pfam; PF10153; Efg1; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Nucleus; Reference proteome; rRNA processing.
FT   CHAIN           1..286
FT                   /note="rRNA-processing protein EFG1"
FT                   /id="PRO_0000330270"
FT   REGION          1..57
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          167..213
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          259..286
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          53..103
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   286 AA;  32500 MW;  3E4275183FA5E679 CRC64;
     MPADKKQRKG AHPYRKPRPN PSDPSSSDKP ARPKPTHRIP ATEARDGAGI PGLSKLKSSI
     RQTKRLLAKE NLEPGLRVST QRRLTSLEAD LAAAERREVE RKNGAKYHKV KFFERQKLVR
     LIKRFKRKLL DSETSSKKRS KHEEELLDAR IMLNYVLHYP NTQKYISLFP SNPNQTEDED
     DDDDSSKPKL KLPPLLHPVP STEECEKMDK PTKRRYDLLL ETKRLMEESK LKSEPETDLK
     KGQVDGVVVG LGADVQIGLG DKKEAKQNAA QGTGEEEDDF FESGDE