ID   ECNB_ECOLI              Reviewed;          48 AA.
AC   P0ADB7; P56549; Q2M6F5;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Entericidin B;
DE   Flags: Precursor;
GN   Name=ecnB; Synonyms=yjeU; OrderedLocusNames=b4411, JW4108;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12 / CS520;
RX   PubMed=9677290; DOI=10.1006/jmbi.1998.1894;
RA   Bishop R.E., Leskiw B.K., Hodges R.S., Kay C.M., Weiner J.H.;
RT   "The entericidin locus of Escherichia coli and its implications for
RT   programmed bacterial cell death.";
RL   J. Mol. Biol. 280:583-596(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=7610040; DOI=10.1093/nar/23.12.2105;
RA   Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R.;
RT   "Analysis of the Escherichia coli genome VI: DNA sequence of the region
RT   from 92.8 through 100 minutes.";
RL   Nucleic Acids Res. 23:2105-2119(1995).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- FUNCTION: Plays a role in the bacteriolysis. Is activated under
CC       conditions of high osmolarity by the factor sigma S. Entericidin A
CC       functions as an antidote.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor.
CC   -!- SIMILARITY: Belongs to the EcnA/EcnB lipoprotein family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U21726; AAC46454.1; -; Genomic_DNA.
DR   EMBL; U14003; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; U00096; AAT48242.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE78151.1; -; Genomic_DNA.
DR   RefSeq; WP_000239596.1; NZ_STEB01000014.1.
DR   RefSeq; YP_026284.1; NC_000913.3.
DR   AlphaFoldDB; P0ADB7; -.
DR   BioGRID; 4261133; 134.
DR   STRING; 511145.b4411; -.
DR   TCDB; 9.B.13.1.1; the putative pore-forming entericidin (ecn) family.
DR   jPOST; P0ADB7; -.
DR   PaxDb; P0ADB7; -.
DR   PRIDE; P0ADB7; -.
DR   EnsemblBacteria; AAT48242; AAT48242; b4411.
DR   EnsemblBacteria; BAE78151; BAE78151; BAE78151.
DR   GeneID; 2847737; -.
DR   GeneID; 67414767; -.
DR   KEGG; ecj:JW4108; -.
DR   KEGG; eco:b4411; -.
DR   PATRIC; fig|1411691.4.peg.2551; -.
DR   EchoBASE; EB4091; -.
DR   eggNOG; COG5510; Bacteria.
DR   HOGENOM; CLU_193827_2_0_6; -.
DR   PhylomeDB; P0ADB7; -.
DR   BioCyc; EcoCyc:MON0-1563; -.
DR   PRO; PR:P0ADB7; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0016020; C:membrane; IDA:EcoCyc.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009636; P:response to toxic substance; IEA:InterPro.
DR   InterPro; IPR012556; Entericidin.
DR   Pfam; PF08085; Entericidin; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   PEPTIDE         22..48
FT                   /note="Entericidin B"
FT                   /id="PRO_0000018170"
FT   LIPID           22
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000305"
FT   LIPID           22
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   48 AA;  4810 MW;  9814A908CA6A70CC CRC64;
     MVKKTIAAIF SVLVLSTVLT ACNTTRGVGE DISDGGNAIS GAATKAQQ