DRP4A_ARATH
ID DRP4A_ARATH Reviewed; 301 AA.
AC Q9ZP56;
DT 21-MAR-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Putative dynamin-related protein 4A;
GN Name=DRP4A; OrderedLocusNames=At1g60530; ORFNames=F8A5.7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14750516; DOI=10.1023/b:plan.0000007000.29697.81;
RA Hong Z., Bednarek S.Y., Blumwald E., Hwang I., Jurgens G., Menzel D.,
RA Osteryoung K.W., Raikhel N.V., Shinozaki K., Tsutsumi N., Verma D.P.S.;
RT "A unified nomenclature for Arabidopsis dynamin-related large GTPases based
RT on homology and possible functions.";
RL Plant Mol. Biol. 53:261-265(2003).
CC -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC superfamily. Dynamin/Fzo/YdjA family. {ECO:0000255|PROSITE-
CC ProRule:PRU01055}.
CC -!- CAUTION: Could be the product of a pseudogene. Lacks the GED domain,
CC which is a conserved feature of the family. {ECO:0000305}.
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DR EMBL; AC002292; AAB71957.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33695.1; -; Genomic_DNA.
DR PIR; E96630; E96630.
DR RefSeq; NP_176253.1; NM_104737.1.
DR AlphaFoldDB; Q9ZP56; -.
DR SMR; Q9ZP56; -.
DR STRING; 3702.AT1G60530.1; -.
DR PaxDb; Q9ZP56; -.
DR PRIDE; Q9ZP56; -.
DR ProteomicsDB; 224368; -.
DR EnsemblPlants; AT1G60530.1; AT1G60530.1; AT1G60530.
DR GeneID; 842348; -.
DR Gramene; AT1G60530.1; AT1G60530.1; AT1G60530.
DR KEGG; ath:AT1G60530; -.
DR Araport; AT1G60530; -.
DR TAIR; locus:2036601; AT1G60530.
DR eggNOG; KOG0446; Eukaryota.
DR HOGENOM; CLU_008964_3_2_1; -.
DR InParanoid; Q9ZP56; -.
DR OMA; ISEMIMH; -.
DR OrthoDB; 559299at2759; -.
DR PhylomeDB; Q9ZP56; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9ZP56; differential.
DR Genevisible; Q9ZP56; AT.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd08771; DLP_1; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR022812; Dynamin.
DR InterPro; IPR001401; Dynamin_GTPase.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11566; PTHR11566; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR PRINTS; PR00195; DYNAMIN.
DR SMART; SM00053; DYNc; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
PE 5: Uncertain;
KW GTP-binding; Nucleotide-binding; Reference proteome.
FT CHAIN 1..301
FT /note="Putative dynamin-related protein 4A"
FT /id="PRO_0000415906"
FT DOMAIN 59..301
FT /note="Dynamin-type G"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01055"
FT REGION 69..76
FT /note="G1 motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01055"
FT REGION 94..96
FT /note="G2 motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01055"
FT REGION 168..171
FT /note="G3 motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01055"
FT REGION 237..240
FT /note="G4 motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01055"
FT REGION 270
FT /note="G5 motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01055"
FT BINDING 69..76
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 168..172
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 237..240
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
SQ SEQUENCE 301 AA; 32883 MW; 04F94951E57EBF50 CRC64;
MGGSKMSNDY EIDVEAGMSS LSIVNTPIEA PIVSSYNDRI RPLLDTVDRL RNLNVMREGI
QLPTIVVVGD QSSGKSSVLE SLAGINLPRG QGICTRVPLV MRLQRSSSPE PEIWLEYSDK
VVPTDEEHVA EAICAATDVI AGTGEGVSDT PLTLSVKKNN VPDLTMVDLP GITRVPVNGQ
PENIYEQISR MIMKYIEPQE SIILNVLSAT VDFTTCESIR MSRQVDKTGE RTLAVVTKAD
MAPEGLLQKV TADDVSIGLG YICVRNRIGE ETYEEARVQE DLLFRTHPLL SLIDGDIVGI
L
