ID   DMC1_LILLO              Reviewed;         349 AA.
AC   P37384;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Meiotic recombination protein DMC1 homolog;
GN   Name=LIM15;
OS   Lilium longiflorum (Trumpet lily).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Liliales; Liliaceae; Lilium.
OX   NCBI_TaxID=4690;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Flower bud;
RX   PubMed=7584025; DOI=10.1093/dnares/1.1.15;
RA   Kobayashi T., Kobayashi E., Sato S., Hotta Y., Miyajima N., Tanaka A.,
RA   Tabata S.;
RT   "Characterization of cDNAs induced in meiotic prophase in lily
RT   microsporocytes.";
RL   DNA Res. 1:15-26(1994).
CC   -!- FUNCTION: May participate in meiotic recombination.
CC   -!- SUBUNIT: Double stacked ring-shaped homooctamer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the RecA family. DMC1 subfamily. {ECO:0000305}.
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DR   EMBL; D21821; BAA04845.1; -; mRNA.
DR   PIR; JC2214; JC2214.
DR   AlphaFoldDB; P37384; -.
DR   SMR; P37384; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000150; F:DNA strand exchange activity; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; IEA:InterPro.
DR   CDD; cd01123; Rad51_DMC1_radA; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR011940; Dmc1.
DR   InterPro; IPR013632; DNA_recomb/repair_Rad51_C.
DR   InterPro; IPR016467; DNA_recomb/repair_RecA-like.
DR   InterPro; IPR010995; DNA_repair_Rad51/TF_NusA_a-hlx.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR033925; Rad51_DMC1_RadA.
DR   InterPro; IPR020588; RecA_ATP-bd.
DR   InterPro; IPR020587; RecA_monomer-monomer_interface.
DR   Pfam; PF08423; Rad51; 1.
DR   PIRSF; PIRSF005856; Rad51; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF47794; SSF47794; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02238; recomb_DMC1; 1.
DR   PROSITE; PS50162; RECA_2; 1.
DR   PROSITE; PS50163; RECA_3; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Cell cycle; DNA-binding; Meiosis; Nucleotide-binding; Nucleus.
FT   CHAIN           1..349
FT                   /note="Meiotic recombination protein DMC1 homolog"
FT                   /id="PRO_0000122921"
FT   BINDING         138..145
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
FT   BINDING         240
FT                   /ligand="dsDNA"
FT                   /ligand_id="ChEBI:CHEBI:4705"
FT                   /evidence="ECO:0000250|UniProtKB:Q14565"
FT   BINDING         240
FT                   /ligand="ssDNA"
FT                   /ligand_id="ChEBI:CHEBI:9160"
FT                   /evidence="ECO:0000250|UniProtKB:Q14565"
FT   BINDING         243
FT                   /ligand="ssDNA"
FT                   /ligand_id="ChEBI:CHEBI:9160"
FT                   /evidence="ECO:0000250|UniProtKB:Q14565"
FT   BINDING         246
FT                   /ligand="dsDNA"
FT                   /ligand_id="ChEBI:CHEBI:4705"
FT                   /evidence="ECO:0000250|UniProtKB:Q14565"
FT   BINDING         246
FT                   /ligand="ssDNA"
FT                   /ligand_id="ChEBI:CHEBI:9160"
FT                   /evidence="ECO:0000250|UniProtKB:Q14565"
FT   BINDING         252
FT                   /ligand="dsDNA"
FT                   /ligand_id="ChEBI:CHEBI:4705"
FT                   /evidence="ECO:0000250|UniProtKB:Q14565"
FT   BINDING         252
FT                   /ligand="ssDNA"
FT                   /ligand_id="ChEBI:CHEBI:9160"
FT                   /evidence="ECO:0000250|UniProtKB:Q14565"
FT   BINDING         320
FT                   /ligand="ssDNA"
FT                   /ligand_id="ChEBI:CHEBI:9160"
FT                   /evidence="ECO:0000250|UniProtKB:Q14565"
SQ   SEQUENCE   349 AA;  38272 MW;  CDA444A1166DBEC6 CRC64;
     MVDVKFEERR FESPGQLQLL DRQEAEEEEE DCFESIDKLI SQGINAGDVK KLQDAGIYTC
     NGLMMHTKKN LTGIKGLSEA KVDKICEAAE KLVNVGYITG SDVLLKRKSV IRITTGSQAL
     DELLGGGIET LQITEAFGEF RSGKTQIAHT LCVSTQLPVS MHGGNGKVAY IDTEGTFRPD
     RIVPIAERFG MDASAVLDNI IYARAYTYEH QYNLLLALAA KMSEEPFRLL IVDSVIALFR
     VDFSGRGELA ERQQKLAQML SRLTKIAEEF NVAVYMTNQV IADPGGGMFI SDPKKPAGGH
     VLAHAATVRL MLRKGKGEQR VCKIFDAPNL PESEAVFQIT PGGVADAKD