B-Raf IN 8

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B-Raf IN 8

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1215313-19-1

B-Raf IN 8 (compound 7g) 是一种有效的B-Raf抑制剂，其IC₅₀为 70.65 nM。B-Raf IN 8 对肝细胞癌 (HEPG-2)、结肠癌 (HCT-116)，乳腺癌 (MCF-7) 和人前列腺癌 (PC-3) 细胞表现出较强的抗肿瘤活性，IC₅₀值分别为9.78、13.78、18.52 和 29.85 μM。

生物活性

B-Raf IN 8 (compound 7g) is a potentB-Rafinhibitor, with anIC₅₀of 70.65 nM. B-Raf IN 8 exhibits antitumor activity against hepatocellular carcinoma (HEPG-2), colon carcinoma (HCT-116), mammary gland (MCF-7) and human prostatecancer(PC-3) cells, withIC₅₀values of 9.78, 13.78, 18.52 and 29.85 μM^[1].

IC₅₀& Target

B-Raf

70.65 ± 0. nM (IC₅₀)

分子量

307.35

Formula

C₁₈H₁₇N₃O₂

CAS 号

1215313-19-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.