Meloxicam sodium 是一种非甾体类抗炎剂,能够有效抑制COX的活性,对 COX-2 和 COX-1 的IC50值分别为 0.49 μM 和 36.6 μM。
生物活性 | Meloxicam sodium is a non-steroidal anti-inflammatory agent, inhibitsCOXactivity, withIC50s of 0.49 μM and 36.6 μM forCOX-2andCOX-1, respectively[1]. |
IC50& Target | COX-2 0.49 μM (IC50) | COX-1 36.6 μM (IC50) | MMP-2 |
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体外研究 (In Vitro) | Meloxicam sodium (0.25 μg/mL) decreases CF41.Mg cell migration and invasion, induces decrease in MMP-2 expression, and increases β-catenin phophorylation in CF41.Mg cells, but does not affect the CF41.Mg cell apoptosis[2].
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |