N-Benzoyl-(2R,3S)-3-phenylisoserine是紫杉醇C-13的侧链,对紫杉醇较强的抗肿瘤活性至关重要。
Cas No. | 132201-33-3 |
别名 | N-苯甲酰基-(2R,3S)-3-苯基异丝氨酸 |
Canonical SMILES | O=C(C1=CC=CC=C1)N[C@](C2=CC=CC=C2)([H])[C@@H](O)C(O)=O |
分子式 | C16H15NO4 |
分子量 | 285.29 |
溶解度 | DMSO : ≥ 160 mg/mL (560.83 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | N-Benzoyl-(2R,3S)-3-phenylisoserine is a Taxol C-13 Side Chain and crucial for the strong antitumor activity of Taxol[1]. [1]. Iwao Ojima, et al. Efficient and Practical Asymmetric Synthesis of the Taxol C-13 Side Chain, N-Benzoyl-(2R,3S)-3-phenylisoserinea,n d Its Analogues via Chiral3-Hydroxy-4-aryl-&lactams through Chiral Ester Enolate-Imine Cyclocondensation. |