Valategrast hydrochloride (R-411) 是一种有效的整联蛋白α4β1 (VLA-4)和α4β7双重拮抗剂。Valategrast hydrochloride 可用于慢性阻塞性肺疾病 (COPD) 和哮喘的研究。
| 生物活性 | Valategrast hydrochloride (R-411) is a potentintegrinα4β1 (VLA-4)andα4β7dual antagonist. Valategrast hydrochloride has the potential for Chronic obstructive pulmonary disease (COPD) and asthma treatment[1][2]. |
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体外研究
(In Vitro) | Valategrast (hydrochloride) contains a common l-phenylalanine-N-aroyl motif where the carboxylic acid is responsible for binding to the metal ion in the metal-ion-dependent adhesion site (MIDAS)[2].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
