HSP90-IN-14

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HSP90-IN-14

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1995132-67-6

HSP90-IN-14 (compound 4) 是一种有效的Hsp90(热休克蛋白 90) 抑制剂，其K_d为 0.26 μM。HSP90-IN-14 在 MDCK 细胞中表现出抗流感病毒活性，对 A/H3N2、A/H1N1 和 B 型流感病毒的EC₅₀值分别为 2.6、3.9 和 17 μM.

生物活性

HSP90-IN-14 (compound 4) is a potentHsp90(heat shock protein 90) inhibitor, with aK_dof 0.26 μM. HSP90-IN-14 showsanti-influenzavirus activity in MDCK cells, withEC₅₀values of 2.6, 3.9, and 17 μM for influenza A/H3N2, A/H1N1, and B, respectively^[1].

IC₅₀& Target

HSP90β

0.26 ± 0.0 μM (Kd)

体外研究
(In Vitro)

HSP90-IN-14 (compound 4) (50 μM) inhibits influenza virus-induced cytopathic effect at non-toxic concentrations^[1].

分子量

399.21

Formula

C₁₄H₈Cl₂N₄O₄S

CAS 号

1995132-67-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.