Monobutylphthalate是邻苯二甲酸二丁酯(DBP)的主要代谢物,具有抗雄激素作用。Monobutylphthalate是一种胚胎毒物。
Cas No. | 131-70-4 |
别名 | 邻苯二甲酸单丁酯 |
Canonical SMILES | O=C(O)C1=CC=CC=C1C(OCCCC)=O |
分子式 | C12H14O4 |
分子量 | 222.24 |
溶解度 | DMSO: 100 mg/mL (449.96 mM) |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant[1][2]. [1]. van Dartel DA, et al. Early gene expression changes during embryonic stem cell differentiation into cardiomyocytes and their modulation by monobutyl phthalate. Reprod Toxicol. 2009 Apr;27(2):93-102.
[2]. Ema M, et al. Antiandrogenic effects of dibutyl phthalate and its metabolite, monobutyl phthalate, in rats. Congenit Anom (Kyoto). 2002 Dec;42(4):297-308. |