Phen-DC3 是一个G4特异性配体,可以抑制解旋酶FANCJ和DinG且IC50s 值分别为 65±6 和 50±10 nM。
| 生物活性 | Phen-DC3 is aG-quadruplex(G4) specific ligand which can inhibitFANCJandDinGhelicases withIC50s of 65±6 and 50±10 nM, respectively. |
| IC50& Target | IC50: 65±6 nM (G4 substrate, FANCJ helicase), 50±10 nM (G4 substrate, DinG helicases)[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
| 溶解性数据 | In Vitro: DMSO : ≥ 34 mg/mL(61.75 mM) *"≥" means soluble, but saturation unknown. 配制储备液 | 1 mM | 1.8162 mL | 9.0808 mL | 18.1617 mL | | 5 mM | 0.3632 mL | 1.8162 mL | 3.6323 mL | | 10 mM | 0.1816 mL | 0.9081 mL | 1.8162 mL |
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