SB 258719 hydrochloride 是一种选择性 5-HT7 受体拮抗剂，对受体具有高亲和力 (pKi=7.5)。
| Cas No. | 1217674-10-6 |
| 化学名 | (R)-N,3-dimethyl-N-(4-(4-methylpiperidin-1-yl)butan-2-yl)benzenesulfonamide hydrochloride |
| Canonical SMILES | CC1CCN(CC[C@@](N(S(C2=CC=CC(C)=C2)(=O)=O)C)([H])C)CC1.Cl |
| 分子式 | C18H30N2O2S.HCl |
| 分子量 | 374.97 |
| 溶解度 | <37.5mg/ml in DMSO;<37.5mg/ml in Water |
| 储存条件 | Desiccate at RT |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | SB 258719 is a selective 5-HT7 receptor antagonist with a pKi of 7.5. References:
[1]. Thomas DR, et al. Functional characterisation of the human cloned 5-HT7 receptor (long form); antagonist profile of SB-258719. Br J Pharmacol. 1998 Jul;124(6):1300-6. |
