DC10SMe 是一种DNA烷化剂,可用于合成抗体偶联药物 (ADC)。DC10SMe 对 Ramos,Namalwa 和 HL60/s 癌细胞的 IC50值分别为 15 pM,12 pM 和 12 pM。
生物活性 | DC10SMe is aDNA alkylator, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC10SMe exhibits IC50s of 15 pM, 12 pM, and 12 pM for Ramos, Namalwa, and HL60/scancercells, respectively[1]. |
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体外研究 (In Vitro) | DC10SMe is a active cyclopropyl form. DC10SMe undergoes N-3 alkylation with an adenine residue and thus form a DNA adduct[1].
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |