ROS kinases-IN-1

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ROS kinases-IN-1

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CAS NO:

370096-57-4

ROS kinases-IN-1 (pag 98) 是一种ROS酪氨酸激酶抑制剂，IC₅₀值为 1.22 μM。ROS kinases-IN-1 具有抗肿瘤活性。

生物活性

ROS kinases-IN-1 (pag 98) is aROS tyrosine kinaseinhibitor withIC₅₀value of 1.22 μM. ROS kinases-IN-1 shows anti-tumor activity^[1].

IC₅₀& Target

IC₅₀: 1.22 μM (ROS kinase)^[1]

体外研究
(In Vitro)

ROS kinases-IN-1 (1-100 μM; 1 d) inhibits the growth of cervical cancer cell and glioblastoma cells^[1].

Cell Viability Assay^[1]

Cell Line:	HeLa, U138, U87, LN18, and U118 cells
Concentration:	1, 10, and 100 μM
Incubation Time:	one day
Result:	Showed EC₅₀s for HeLa, U138, U87, LN18, and U118 cells of 20, 8, 8, 12, and 7 μM, respectively.

分子量

328.37

性状

Solid

Formula

C₂₀H₁₆N₄O

CAS 号

370096-57-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式