TRAF6 peptide

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TRAF6 peptide

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

852805-92-6

TRAF6 peptide 是一种特异性的TRAF6-p62相互作用抑制剂。TRAF6 peptide 能消除 NGF 依赖性TrkA泛素化。TRAF6 peptide 在诸如阿尔茨海默症 (AD)、帕金森、ALS、头部外伤、癫痫和中风等神经系统性疾病中具有较好的研究潜力。

生物活性

TRAF6 peptide is a specificTRAF6-p62inhibitor. TRAF6 peptide potently abrogates NGF-dependentTrkAubiquitination. TRAF6 peptide has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke^[1].

体外研究
(In Vitro)

TRAF6 peptide (150 μM; 5 h) blocks the interaction of p62 with TRAF6 in PC12 cells^[1].
TRAF6 peptide eliminates TRAF6 and UbcH7 from interacting with TrkA and can ffectively abolish NGF-dependent ubiquitination of TrkA in vitro^[1].

Western Blot Analysis^[1]

Cell Line:	PC12 cells
Concentration:	150 μM
Incubation Time:	5 h
Result:	Inhibited the interaction of p62 with TRAF6 by immunoprecipitating TRA F6.

分子量

3161.64

Formula

C₁₄₅H₂₃₈N₃₄O₄₄

CAS 号

852805-92-6

Sequence Shortening

AAVALLPAVLLALLAPESASGPSEDPSVNFLK

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.