MCH(human,mouse,rat)

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CAS NO:

128315-56-0

MCH (human, mouse, rat) 是一种有效的MCH-R 的肽激动剂，与 MCH1R 和 MCH2R 结合的IC₅₀值分别为 0.3nM 和 1.5 nM。MCH (human, mouse, rat) 对 CHO 细胞系中 MCH-2R 高度敏感，通过 FLIPR 监测细胞内钙动员，显示出功能性激活 MCH-1R 和 MCH-2R 的EC₅₀值对分别为 3.9 nM 和 0.1 nM。

生物活性	MCH (human, mouse, rat) is a potent peptide agonist ofMCH-Rand exhibits bindingIC₅₀values of 0.3nM and 1.5 nM for MCH1R and MCH2R, respectively. MCH (human, mouse, rat) is a highly sensitive to MCH-2R in a CHO cell line and monitoring mobilization of intracellular calcium with FLIPR, exhibits functional activationEC₅₀values of 3.9 nM and 0.1nM for human MCH-1R and MCH-2R, respectively^[1].
IC₅₀& Target	Binding IC50: 0.3 nM (MCH1R) IC50: 1.5 nM (MCH1R)^[1]
分子量	2386.84
Formula	C₁₀₅H₁₆₀N₃₀O₂₆S₄
CAS 号	128315-56-0
Sequence Shortening	DFDMLRCMLGRVYRPCWQV (Disulfide bridge:Cys7-Cys16)
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.