3-Nitropropionic acid (β-Nitropropionic acid) 是琥珀酸脱氢酶的不可逆抑制剂。
| Cas No. | 504-88-1 |
| 别名 | 3-硝基丙酸; β-Nitropropionic acid; Bovinocidin |
| 化学名 | 3-nitropropanoic acid |
| Canonical SMILES | OC(CC[N+]([O-])=O)=O |
| 分子式 | C3H5NO4 |
| 分子量 | 119.08 |
| 溶解度 | ≥ 6mg/mL in DMSO |
| 储存条件 | 4°C, away from moisture and light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 3-Nitropropanoic acid is an irreversible inhibitor of succinate dehydrogenase. References:
[1]. Huang LS, et al. 3-nitropropionic acid is a suicide inhibitor of mitochondrial respiration that, upon oxidation by complex II, forms a covalent adduct with a catalytic base arginine in the active site of the enzyme. J Biol Chem. 2006 Mar 3;281(9):5965-72. |
