ITK antagonist (compound 10 n) 是一种有效且选择性的，具有口服活性的ITK(白细胞介素-2诱导型T细胞激酶) 拮抗剂 (在不同的分析中,IC50=1和20 nM)。ITK antagonist 抑制胰岛素受体激酶 (IRK)，IC50为 160 nM。
| 生物活性 | ITKantagonist (compound 10 n) is a potent, orally active and selectiveITK(Interleukin-2 inducible T-cell kinase) antagonist (IC50=1 and 20 nM in different assays).ITKantagonist inhibitsinsulin receptorkinase (IRK) with an IC50of 160 nM[1]. |
体外研究
(In Vitro) | ITK antagonist inhibits DT40 cell (IC50=4 nM) and shows IL-2 inhibition (IC50=20 nM)[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
