G3-C12 is a galectin-3 binding peptide, withK_dof 88 nM, and shows anticancer activity.

Kd: 88 nM (Galectin-3)^[1]

G3-C12 is a galectin-3 binding peptide, with high affinity (K_d) of 88 nM, but shows no affinity for other galectin family members or to other lectins. G3-C12 bearing opolymers N-(2-hydroxypropyl)methacrylamide (HPMA) potently and selectively targets colorectal cancer (CRC) tumour cells over-expressing galectin-3 and displays superior targetability to galectin-3 compared to the galactose bearing copolymer^[1].

1758.98

Solid

C₇₄H₁₁₅N₂₃O₂₃S₂

848301-94-0

Ala-Asn-Thr-Pro-Cys-Gly-Pro-Tyr-Thr-His-Asp-Cys-Pro-Val-Lys-Arg

ANTPCGPYTHDCPVKR

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)