Boc-NH-PEG1-CH2CH2COOH 是一种可降解 (cleavable) 的含 1 个单元 PEG 的 ADC linker，同时也是 PROTAC linker，属于 PEG 和 Alkyl/ether 类，可用于合成抗体偶联药物 (ADC) 和 PROTAC。
| Cas No. | 1260092-44-1 |
| 分子式 | C10H19NO5 |
| 分子量 | 233.26 |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Boc-NH-PEG1-CH2CH2COOH is a cleavable (1 unit PEG) ADC linker and also aPEG- andAlkyl/ether-basedPROTAC linkercan be used in the synthesis of antibody-drug conjugates (ADCs) or PROTACs[1][2]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
