MtTMPK-IN-1 (compound 3) 一种有效的分支杆菌胸苷酸激酶 (MtbTMPK)抑制剂,IC50为 2.5 μM。MtTMPK-IN-1 对MtbH37Rv 具有中等至微弱的抑制活性,对人成纤维细胞 MRC-5 具有低细胞毒性。MtTMPK-IN-1 可用于结核病的研究。
生物活性 | MtTMPK-IN-1 (compound 3) is a potentMycobacterium tuberculosisthymidylate kinase (MtTMPK)inhibitor with anIC50value of 2.5 μM. MtTMPK-IN-1 has moderate to weak activity againstMtbH37Rv and low cytotoxicity in human fibroblast cells MRC-5. MtTMPK-IN-1 can be used for researching tuberculosis[1]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |