Ac-FEID-CMK TFA 是一种有效的斑马鱼特异性GSDMEb衍生肽抑制剂。Ac-FEID-CMK TFA 可减轻感染性休克的死亡率和肾损伤。Ac-FEID-CMK TFA 在体内可抑制焦亡，减轻败血性 AKI (急性肾损伤)。Ac-FEID-CMK TFA 可抑制 caspy2 介导的非典型炎症小体通路。
| 生物活性 | Ac-FEID-CMK TFA is a potent zebrafish-specificGSDMEb-derived peptideinhibitor.
Ac-FEID-CMK TFA can attenuate the mortality and kidney injury during septic shock. Ac-FEID-CMK TFA inhibitspyroptosisand attenuates septic AKI (acute kidney injury)in vivo. Ac-FEID-CMK TFA can suppress the caspy2-mediated noncanonical inflammasome pathway[1]. |
| 分子量 | |
| 性状 | |
| Formula | |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | -20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
