SGD-1910 是抗体偶联药物的一部分 (drug-linker conjugate for ADC),它由 PBD (一种细胞毒性 DNA 交联剂) 和可降解 (cleavable) 的 MC-Val-Ala 连接而成。
生物活性 | SGD-1910 is adrug-linker conjugate for ADCby using the antitumorantibiotic, pyrrolobenzodiazepine (PBD, a cytotoxic DNA crosslinking), linked via thecleavablelinker MC-Val-Ala[1]. |
IC50& Target[1] | |
体外研究 (In Vitro) | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | -20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |