| CAS NO: | 1404-19-9 |
| 生物活性 | Oligomycin, an antifungalantibiotic, is an inhibitor ofH+-ATP-synthase. Oligomycin blocks oxidative phosphorylation and the electron transport chain. Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells[1][2][3][4]. |
| 体外研究 (In Vitro) | Oligomycin, inhibitor of the F0 part of H+-ATP-synthase, suppresses the TNF-induced apoptosis[1]. |
| 性状 | Solid |
| CAS 号 | 1404-19-9 |
| 中文名称 | 寡霉素 |
| 结构分类 |
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| 来源 | Streptomyces |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | -20°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
| 溶解性数据 | In Vitro: Ethanol : 30 mg/mL(Need ultrasonic and warming) DMSO : 20 mg/mL(Need ultrasonic and warming) |
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