Fomivirsen (ISIS-2922 free base) 是一种反义 21 mer 磷酸硫寡核苷酸。Fomivirsen 是一种用于巨细胞病毒视网膜炎 (cytomegalovirus retinitis (CMV)) 研究的抗病毒试剂。Fomivirsen 结合并降解 CMV immediate-early 2 蛋白的 mRNA，从而抑制病毒增殖。
| 生物活性 | Fomivirsen (ISIS-2922 free base) is an antisense 21 mer phosphorothioate oligonucleotide. Fomivirsen is anantiviral agentthat is usedcytomegalovirus retinitis (CMV)research, incluiding in AIDs. Fomivirsen binds to and degrades the mRNAs encodingCMVimmediate-early 2 protein, thus inhibiting virus proliferation[1][2]. |
| 分子量 | |
| Formula | |
| CAS 号 | |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
