Echinatin 是从中草药甘草中分离得到，查尔酮，具有保肝和抗炎作用。Echinatin 在水溶液中经过电子转移 (ET) 和质子转移 (PT) 引起抗氧化作用。 在大鼠中，Echinatin 可以被快速吸收和消除并广泛分布，绝对生物利用度约为 6.81％。
| Cas No. | 34221-41-5 |
| 别名 | 刺甘草查尔酮 |
| Canonical SMILES | O=C(C1=CC=C(O)C=C1)/C=C/C2=CC=C(O)C=C2OC |
| 分子式 | C16H14O4 |
| 分子量 | 270.28 |
| 溶解度 | DMSO: 250 mg/mL (924.97 mM) |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Echinatin is a chalcone isolated from the Chinese herbal medicine Gancao with hepatoprotective and anti-inflammatory effects. Echinatin may undergo an electron transfer (ET) and a proton transfer (PT) to cause the antioxidant action in aqueous solution[1]. Echinatin can be quickly absorbed and eliminated and extensively distributed with an absolute bioavailability of approximately 6.81% in Rat[2]. [1]. Liang M, et al. Antioxidant Mechanisms of Echinatin and Licochalcone A. Molecules. 2018 Dec 20;24(1).
[2]. Inoue B, et al. The effects of echinatin and its related compounds on the mitochondrial energy transfer reaction. J Toxicol Sci. 1982 Nov;7(4):245-54. |
