Boc-bipiperidine-ethynylbenzoic acid 是一种 PROTAC linker,属于 alkyl/ether 类。可用于合成 PROTAC 分子 ARD-61。
Cas No. | 2308497-81-4 |
分子式 | C24H32N2O4 |
分子量 | 412.52 |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Boc-bipiperidine-ethynylbenzoic acid is an Alkyl/ether-basedPROTAC linkercan be used in the synthesis of ARD-61[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |